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自闭症谱系障碍儿童的注意缺陷多动障碍症状。

Attention Deficit Hyperactivity Disorder Symptoms in Young Children with Autism Spectrum Disorder.

机构信息

Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore, Maryland, USA.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Autism Res. 2021 Jan;14(1):182-192. doi: 10.1002/aur.2414. Epub 2020 Oct 19.

Abstract

The purpose of the current study was to examine the prevalence of attention deficit hyperactivity disorder (ADHD) symptoms among young children with autism spectrum disorder (ASD), child and parent-related demographic and clinical correlates of ADHD symptoms, and the relationships between co-occurring mental health problems and ADHD symptoms. Data for this cross-sectional study came from 979 toddlers and preschoolers, ages 1.5-5 years, with ASD. The primary outcome, ADHD symptoms, was measured using the Child Behavior Check List 1.5-5 (CBCL). Additional information from the medical record included demographics, parenting stress, and Autism Diagnostic Observation Schedule Second Edition. Descriptive and bivariate (ANOVA, Chi-Square) statistics and multivariate, multinomial regression analyses were used to examine demographic and clinical differences between low, moderate, and high ADHD symptom groups, as defined by 2 ADHD-related subscales. There were 418 (43%) children in the low ADHD symptom group, 294 (30%) in the moderate ADHD symptom group, and 267 (27%) in the high ADHD symptom group. Those with high ADHD symptoms were less likely to be Black or Hispanic and less likely to have parents with a graduate-level education compared to those with low ADHD symptoms. Parenting stress and all CBCL DSM-oriented subscales were positively associated with increasing ADHD symptoms. Among young children with ASD, ADHD symptoms were highly prevalent. The presence of ADHD symptoms was associated with increasing parenting stress and greater levels of other psychopathologies. These data suggest that young children with ASD should be evaluated for ADHD, and mental health as a whole. LAY SUMMARY: We investigated attention deficit hyperactivity disorder (ADHD) symptoms in toddlers and preschoolers with autism spectrum disorder (ASD) from a large sample with diverse race and socioeconomic background. In our study, we found that ADHD symptoms are highly prevalent in young children with ASD and are associated with increasing parenting stress and greater level of other psychopathologies, both internalizing and externalizing problems.

摘要

本研究旨在调查自闭症谱系障碍(ASD)幼儿中注意缺陷多动障碍(ADHD)症状的流行率、ADHD 症状与儿童和家长相关的人口统计学和临床相关性,以及共患精神健康问题与 ADHD 症状之间的关系。本横断面研究的数据来自 979 名年龄在 1.5-5 岁的 ASD 幼儿和学龄前儿童。主要结果为使用儿童行为检查表 1.5-5(CBCL)测量的 ADHD 症状。病历中还包括人口统计学、育儿压力和自闭症诊断观察量表第二版的信息。采用描述性和双变量(方差分析、卡方检验)统计和多变量、多项回归分析,根据 2 个与 ADHD 相关的子量表,检查低、中、高 ADHD 症状组之间的人口统计学和临床差异。低 ADHD 症状组有 418 名(43%)儿童,中 ADHD 症状组有 294 名(30%),高 ADHD 症状组有 267 名(27%)。与低 ADHD 症状组相比,高 ADHD 症状组中黑人或西班牙裔儿童比例较低,父母具有研究生学历的比例也较低。育儿压力和所有 CBCL DSM 定向子量表与 ADHD 症状的增加呈正相关。在 ASD 幼儿中,ADHD 症状非常普遍。ADHD 症状的存在与育儿压力的增加以及其他精神病理学的水平的升高有关。这些数据表明,应评估 ASD 幼儿是否存在 ADHD 以及整体心理健康问题。

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