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丹麦腰椎间盘突出症患者终板连接失败的发生率较低。

Low prevalence of end plate junction failure in danish patients with lumbar disc herniation.

机构信息

Spinecenter of Southern Denmark, Lillebælt Hospital, Middelfart, DK5750, Denmark.

University of Southern Denmark, Institute of Regional Health Science Research, Odense, DK5230, Denmark.

出版信息

Sci Rep. 2020 Oct 19;10(1):17652. doi: 10.1038/s41598-020-74690-w.

Abstract

The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study.

摘要

本研究旨在确定丹麦较小腰椎间盘突出症患者中终板连接失败的发生率,并与之前发表的印度数据进行比较。纳入了在大型区域性医院脊柱护理单元就诊的具有腰椎间盘突出症临床表现并伴有神经根病的连续患者,且有近期 MRI 检查结果证实。作为研究的一部分,还进行了额外的 CT 成像,这些图像特别关注终板连接失败。出于伦理原因,将参与者人数保持在最低限度,总共纳入了 26 名患者。发现终板连接失败的发生率(n=5)明显低于之前报道的发生率。我们的发现与之前在印度人群中报道的结果不一致:确实观察到了终板连接失败,但发生率明显较低。我们讨论了导致发现结果差异的潜在原因,并适当关注了当前研究的局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cae/7573575/f0e4786f2697/41598_2020_74690_Fig1_HTML.jpg

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