Inoue Nozomu, Espinoza Orías Alejandro A
Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Orthop Clin North Am. 2011 Oct;42(4):487-99, vii. doi: 10.1016/j.ocl.2011.07.001.
Degenerative changes in the material properties of nucleus pulposus and anulus fibrosus promote changes in viscoelastic properties of the whole disc. Volume, pressure and hydration loss in the nucleus pulposus, disk height decreases and fissures in the anulus fibrosus, are some of the signs of the degenerative cascade that advances with age and affect, among others, spinal function and its stability. Much remains to be learned about how these changes affect the function of the motion segment and relate to symptoms such as low back pain and altered spinal biomechanics.
髓核和纤维环材料特性的退行性变化会促使整个椎间盘的粘弹性特性发生改变。髓核的体积、压力和含水量降低，椎间盘高度减小以及纤维环出现裂隙，这些都是随着年龄增长而出现的退行性级联反应的一些迹象，会影响脊柱功能及其稳定性等。关于这些变化如何影响运动节段的功能以及与腰背痛和脊柱生物力学改变等症状的关系，仍有许多有待了解的地方。
