Chen Mingsheng, Xin Ping, Feng Kaidi, Zhao Tianyu, Yang Xiangdong
Clinical School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan province.
Tianjin University of Traditional Chinese Medicine, Tianjin.
Medicine (Baltimore). 2020 Oct 16;99(42):e22658. doi: 10.1097/MD.0000000000022658.
Ulcerative colitis (UC) is a refractory intestinal disease prone to recurrent attacks, with a high rate of canceration, which seriously affects life treatment. Routine treatment has disadvantages such as long course of treatment, high cost, easy recurrence and limited effectiveness. Clinical practice shows that acupoint catgut embedding therapy has certain therapeutic advantages but lacks evidence of evidence-based medicine. The purpose of this study is to systematically study the effectiveness and safety of acupoint catgut embedding for ulcerative colitis.
Retrieve English database (PubMed, Embase, Web of Science, the Cochrane Library) and Chinese database (CNKI, CDDB, CQVIP, CBM) by computer, and manually retrieve Baidu and Google Academy for randomized controlled trials (RCTs) of acupoint catgut embedding therapy for ulcerative colitis from the time of construction of database to September 2020. Two researchers independently extracted data and evaluated the quality of the literature included in the study, and used RevMan 5.3 software for meta-analysis of the included literature.
The study evaluated the effectiveness and safety of acupoint catgut embedding for ulcerative colitis through efficiency, symptom score, colonoscopy score, mucosal healing rate, recurrence rate, incidence of adverse reactions, etc. CONCLUSION:: This study will provide reliable evidence-based evidence for clinical application of acupoint catgut embedding therapy for ulcerative colitis.
DOI 10.17605/ OSF.IO / 7T4QV.
溃疡性结肠炎（UC）是一种易反复发作的难治性肠道疾病，癌变率高，严重影响生活质量。常规治疗存在疗程长、费用高、易复发及疗效有限等缺点。临床实践表明，穴位埋线疗法具有一定治疗优势，但缺乏循证医学证据。本研究旨在系统评价穴位埋线治疗溃疡性结肠炎的有效性和安全性。
通过计算机检索英文数据库（PubMed、Embase、Web of Science、Cochrane Library）和中文数据库（CNKI、维普、万方、CBM），并手工检索百度和谷歌学术，收集自建库至2020年9月穴位埋线治疗溃疡性结肠炎的随机对照试验（RCT）。两名研究人员独立提取数据并评价纳入研究文献的质量，采用RevMan 5.3软件对纳入文献进行Meta分析。
本研究从有效率、症状积分、结肠镜积分、黏膜愈合率、复发率、不良反应发生率等方面评价穴位埋线治疗溃疡性结肠炎的有效性和安全性。
本研究将为穴位埋线疗法治疗溃疡性结肠炎的临床应用提供可靠的循证依据。
DOI 10.17605/ OSF.IO / 7T4QV。
