Amiel Eyal, Perona-Wright Georgia
Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT, USA.
Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, UK.
Immunology. 2020 Nov;161(3):163-164. doi: 10.1111/imm.13275.
Here we announce the first part of an exciting new series of reviews exploring the impact of immunometabolism in the interaction between host and pathogen, and in the outcome of infection. This collection discusses the links between metabolism and epigenetic control of cell function, post-translation modifications of host proteins that determine protein fate and host cell function, the metabolic determinants of cell migration and immune cell activity, and the tussle for iron as a metabolic mediator of host-pathogen domination. Together these reviews provide engaging new insight into the metabolic signals that guide the dynamic conversation between microbial pathogens and the mammalian hosts they aim to occupy.
在此，我们宣布推出一系列令人兴奋的新综述的第一部分，该系列将探讨免疫代谢在宿主与病原体相互作用以及感染结果中的影响。本论文集讨论了代谢与细胞功能的表观遗传控制之间的联系、决定蛋白质命运和宿主细胞功能的宿主蛋白的翻译后修饰、细胞迁移和免疫细胞活性的代谢决定因素，以及作为宿主 - 病原体主导的代谢介质的铁争夺。这些综述共同为指导微生物病原体与它们试图占据的哺乳动物宿主之间动态对话的代谢信号提供了引人入胜的新见解。
