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石蒜属生物碱的化学与生物活性。(石蒜科)

Chemistry and Biological Activity of Alkaloids from the Genus (Amaryllidaceae).

机构信息

ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.

出版信息

Molecules. 2020 Oct 19;25(20):4797. doi: 10.3390/molecules25204797.

Abstract

Herbert, family Amaryllidaceae, is a small genus of about 20 species that are native to the warm temperate woodlands of eastern Asia, as in China, Korea, Japan, Taiwan, and the Himalayas. For many years, species of have been subjected to extensive phytochemical and pharmacological investigations, resulting in either the isolation or identification of more than 110 Amaryllidaceae alkaloids belonging to different structural types. Amaryllidaceae alkaloids are frequently studied for their interesting biological properties, including antiviral, antibacterial, antitumor, antifungal, antimalarial, analgesic, cytotoxic, and cholinesterase inhibition activities. The present review aims to summarize comprehensively the research that has been reported on the phytochemistry and pharmacology of the genus .

摘要

赫伯特,石蒜科,是一个大约有 20 个物种的小属,原产于东亚温暖的温带林地,如中国、韩国、日本、中国台湾和喜马拉雅山。多年来,一直对进行广泛的植物化学和药理学研究,结果分离或鉴定出属于不同结构类型的超过 110 种石蒜科生物碱。石蒜科生物碱因其有趣的生物特性而经常受到研究,包括抗病毒、抗菌、抗肿瘤、抗真菌、抗疟、镇痛、细胞毒性和胆碱酯酶抑制活性。本综述旨在全面总结该属植物化学和药理学研究的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a88/7587589/839afc9bc052/molecules-25-04797-g001.jpg

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