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来自[具体科名未给出]的七种民族药用植物的抗菌活性。

Antibacterial activities of seven ethnomedicinal plants from family .

作者信息

Harahap Diannita, Niaci Sarah, Mardina Vivi, Zaura Bintang, Qanita Intan, Purnama Agnia, Puspita Kana, Rizki Diva Rayyan, Iqhrammullah Muhammad

机构信息

Department of Biology, Faculty of Science and Technology, Universitas Islam Negeri Ar-Raniry, Banda Aceh, Indonesia.

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.

出版信息

J Adv Pharm Technol Res. 2022 Jul-Sep;13(3):148-153. doi: 10.4103/japtr.japtr_111_22. Epub 2022 Jul 5.

Abstract

Serious threat to human health caused by bacterial infection persists as a global concern. It becomes more serious when the burden of multidrug-resistance bacteria is in the increasing trend. To overcome, researches have been conducted to develop antibacterial agents from plant-derived bioactive compounds. This review article focuses on the antibacterial activities of plant extracts from seven members, namely , , , , , , and . First, ethnomedical uses of the aforementioned plants are discussed and followed by the screening results of related phytochemicals. Among many secondary metabolites contained in the extracts of spp., anonaine, nornuciferine, and liriodenine are common and bioactive. The extracts were reported to have bacteriostatic and bactericidal properties against a wide spectrum of bacteria, including multidrug-resistant , , , , , , , , and . We conclude that investigation on the extracts from spp. could contribute to the development of antibacterial agents that could be used against multidrug-resistant bacteria.

摘要

细菌感染对人类健康造成的严重威胁仍然是一个全球关注的问题。当多重耐药菌的负担呈上升趋势时,这一问题变得更加严重。为了克服这一问题,人们开展了从植物源生物活性化合物开发抗菌剂的研究。这篇综述文章聚焦于七种植物提取物的抗菌活性,这七种植物分别是[此处七种植物名称缺失]。首先,讨论了上述植物的民族药用情况,随后是相关植物化学物质的筛选结果。在[植物名称]提取物所含的众多次生代谢产物中,木兰碱、去甲异喹啉碱和鹅掌楸碱是常见的生物活性成分。据报道,这些提取物对多种细菌具有抑菌和杀菌特性,包括多重耐药的[此处细菌名称缺失]。我们得出结论,对[植物名称]提取物的研究可能有助于开发可用于对抗多重耐药菌的抗菌剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d5f/9355059/ac978cfceab0/JAPTR-13-148-g001.jpg

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