Huang Shao-Shao, Tan Rong-Cai, Kuang Xiao-Lan
Department of Stomatology, Baise People's Hospital. Baise 533000, Guangxi Zhuang Autonomous Region, China. E-mail:
Shanghai Kou Qiang Yi Xue. 2020 Aug;29(4):427-430.
To investigate the effect of Bio-Oss bone powder combined with platelet-rich fibrin on bone mass after implantation-guided bone regeneration in alveolar bone defects.
One hundred and six patients with single anterior tooth loss and labial alveolar bone defect were selected for implant implantation and guided bone regeneration at the same time. Patients in the experimental group (n=53) were treated with Bio-Oss bone powder combined with platelet-rich fibrin and biofilm to guide bone regeneration, while patients in the control group(n=53) were treated with Bio-Oss bone powder combined with biofilm to guide bone regeneration. The success rate of implantation, complication rate, the thickness of labial bone wall and the regeneration of bone defect were observed. Statistical analysis was performed on the data using SPSS 25.0 software package.
There was no significant difference in the success rate of implants between the two groups(96.23% vs 88.68%, P>0.05). The thickness of the labial bone wall of the experimental group 12 months after implantation was significantly higher than that of the control group[(2.72±0.43) mm vs(2.51±0.36) mm], and the thickness of the labial wall of the implant at different sites was significantly greater than that of the control group(P<0.05). Bleeding index [(0.32±0.02) vs (0.42±0.03)], depth of probing [(3.31±0.69) mm vs (4.32±0.95) mm], loss of attachment [(3.06±0.52) mm vs (5.24±1.35) mm] was significantly smaller in the experimental group than in the control group (P<0.05); bone graft height [(2.61±0.52) mm vs (2.31±0.35) mm], osteogenesis height [(2.59±0.32) mm vs (2.01±0.16) mm] was significantly greater in the experimental group than in the control group(P<0.05). There was no significant difference in the incidence of complications between the two groups(1.89% vs 5.66%, P>0.05).
Bio-Oss bone powder combined with platelet-rich fibrin can reduce bone loss and promote bone defect regeneration after guided bone regeneration.
探讨Bio-Oss骨粉联合富血小板纤维蛋白对牙槽骨缺损引导骨再生植入术后骨量的影响。
选取106例单颗前牙缺失且伴有唇侧牙槽骨缺损的患者，同期行种植体植入及引导骨再生术。实验组（n=53）采用Bio-Oss骨粉联合富血小板纤维蛋白及生物膜引导骨再生，对照组（n=53）采用Bio-Oss骨粉联合生物膜引导骨再生。观察种植成功率、并发症发生率、唇侧骨壁厚度及骨缺损区骨再生情况。采用SPSS 25.0软件包对数据进行统计学分析。
两组种植成功率差异无统计学意义（96.23% vs 88.68%，P>0.05）。实验组植入后12个月唇侧骨壁厚度显著高于对照组[（2.72±0.43）mm vs（2.51±0.36）mm]，且不同位点种植体唇侧骨壁厚度均显著大于对照组（P<0.05）。实验组出血指数[（0.32±0.02）vs（0.42±0.03）]、探诊深度[（3.31±0.69）mm vs（4.32±0.95）mm]、附着丧失[（3.06±0.52）mm vs（5.24±1.35）mm]均显著小于对照组（P<0.05）；骨移植高度[（2.61±0.52）mm vs（2.31±0.35）mm]、成骨高度[（2.59±0.32）mm vs（2.01±0.16）mm]均显著大于对照组（P<0.05）。两组并发症发生率差异无统计学意义（1.89% vs 5.66%，P>0.05）。
Bio-Oss骨粉联合富血小板纤维蛋白可减少引导骨再生术后骨量丢失，促进骨缺损区骨再生。
