Park Hyerin, Parys Simon, Tan Jonathan, Entriken Fiona, Hodder Rupert
Colorectal Surgery Unit, Department of Surgery, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
ANZ J Surg. 2021 Mar;91(3):387-391. doi: 10.1111/ans.16394. Epub 2020 Oct 22.
Despite the prevalence of colorectal cancer in the elderly, there has been a lack of recent studies examining surgical outcomes in these patients. Post-operative outcomes of colorectal cancer surgeries in those aged 80 and above will be compared to those younger than 80.
A retrospective study was conducted of adults receiving surgical resections at a single tertiary centre for colorectal cancer diagnosed between January 2017 and December 2019. Patient demographics, mode of presentation, tumour demographics, operative data and post-operative outcomes were investigated.
Of the 326 patients included, 56 were aged 80 and above. Older patients were more likely to be female (P = 0.02), present with surgical emergencies or from other workup rather than through screening (P = 0.002), have more locally advanced cancers (P = 0.009) and receive less neoadjuvant therapy (P = 0.016). Despite this, they had comparable outcomes to those younger than 80 in terms of length of stay (P = 0.21) and rates of complications including mortality (P = 0.67).
With appropriate patient selection and management, elderly patients can achieve comparable post-operative outcomes to their younger counterparts.
尽管老年人大肠癌患病率较高,但近期缺乏针对这些患者手术结果的研究。将80岁及以上患者的结直肠癌手术术后结果与80岁以下患者进行比较。
对2017年1月至2019年12月期间在单一三级中心接受手术切除的成年结直肠癌患者进行回顾性研究。调查患者的人口统计学特征、就诊方式、肿瘤特征、手术数据和术后结果。
在纳入的326例患者中,56例年龄在80岁及以上。老年患者更可能为女性(P = 0.02),因外科急症或其他检查而非筛查就诊(P = 0.002),患有更多局部晚期癌症(P = 0.009),接受新辅助治疗较少(P = 0.016)。尽管如此,他们在住院时间(P = 0.21)和包括死亡率在内的并发症发生率方面(P = 0.67)与80岁以下患者相当。
通过适当的患者选择和管理,老年患者可以获得与年轻患者相当的术后结果。