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独居、孤独感和缺乏情感支持与自杀和自残的关系:英国生物库队列的九年随访研究。

Living alone, loneliness and lack of emotional support as predictors of suicide and self-harm: A nine-year follow up of the UK Biobank cohort.

机构信息

Institute of Health and Wellbeing, University of Glasgow, United Kingdom.

Institute of Health and Wellbeing, University of Glasgow, United Kingdom.

出版信息

J Affect Disord. 2021 Jan 15;279:316-323. doi: 10.1016/j.jad.2020.10.026. Epub 2020 Oct 14.

Abstract

BACKGROUND

The association between loneliness and suicide is poorly understood. We investigated how living alone, loneliness and emotional support were related to suicide and self-harm in a longitudinal design.

METHODS

Between 2006 and 2010 UK Biobank recruited and assessed in detail over 0.5 million people in middle age. Data were linked to prospective hospital admission and mortality records. Adjusted Cox regression models were used to investigate relationships between living arrangements, loneliness and emotional support, and both suicide and self-harm as outcomes.

RESULTS

For men, both living alone (Hazard Ratio (HR) 2.16, 95%CI 1.51-3.09) and living with non-partners (HR 1.80, 95%CI 1.08-3.00) were associated with death by suicide, independently of loneliness, which had a modest relationship with suicide (HR 1.43, 95%CI 0.1.01-2.03). For women, there was no evidence that living arrangements, loneliness or emotional support were associated with death by suicide. Associations between living alone and self-harm were explained by health for women, and by health, loneliness and emotional support for men. In fully adjusted models, loneliness was associated with hospital admissions for self-harm in both women (HR 1.89, 95%CI 1.57-2.28) and men (HR 1.74, 95%CI 1.40-2.16).

LIMITATIONS

Loneliness and emotional support were operationalized using single item measures.

CONCLUSIONS

For men - but not for women - living alone or living with a non-partner increased the risk of suicide, a finding not explained by subjective loneliness. Overall, loneliness may be more important as a risk factor for self-harm than for suicide. Loneliness also appears to lessen the protective associations of cohabitation.

摘要

背景

孤独感与自杀之间的关联尚未得到充分理解。我们通过纵向设计,研究了独居、孤独感和情感支持与自杀和自残之间的关系。

方法

在 2006 年至 2010 年间,英国生物库招募并详细评估了超过 50 万名中年人。数据与前瞻性住院和死亡率记录相关联。采用调整后的 Cox 回归模型,调查了生活安排、孤独感和情感支持与自杀和自残之间的关系。

结果

对于男性,独居(危险比 (HR) 2.16,95%置信区间 (CI) 1.51-3.09)和与非伴侣同住(HR 1.80,95%CI 1.08-3.00)均与自杀死亡独立相关,而孤独感与自杀有一定关系(HR 1.43,95%CI 0.1.01-2.03)。对于女性,没有证据表明生活安排、孤独感或情感支持与自杀死亡有关。对于女性,独居与自残之间的关联可由健康状况解释;对于男性,这种关联可由健康状况、孤独感和情感支持解释。在完全调整的模型中,孤独感与女性(HR 1.89,95%CI 1.57-2.28)和男性(HR 1.74,95%CI 1.40-2.16)因自残住院的风险相关。

局限性

孤独感和情感支持是通过单项措施来衡量的。

结论

对于男性——而不是女性——独居或与非伴侣同住会增加自杀风险,这一发现不能用主观孤独感来解释。总体而言,孤独感可能是自残的一个更重要的风险因素,而不是自杀。孤独感似乎也削弱了同居的保护关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40da/7758739/e3e1fbcf9055/gr1.jpg

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