Hiwale Sujitkumar, Firtion Celine
Philips Research India, Philips Innovation Campus, Nagavara, Bengaluru, Karnataka, India.
Indian J Radiol Imaging. 2020 Apr-Jun;30(2):156-162. doi: 10.4103/ijri.IJRI_167_19. Epub 2020 Jul 13.
The primary objective of this study was to examine the impact of maternal age, parity, gestational age, fetal gender, gestational diabetes mellitus, and pregnancy-induced hypertension on the accuracy of ultrasonography-based fetal weight estimation. The secondary objective was to find the impact of a formula selection on the accuracy of fetal weight estimation.
The inclusion criteria were a live-birth singleton pregnancy and the last ultrasound scan to delivery interval ≤7 days. Fetal weight was estimated using the Hadlock-4 formula. To study the concurrent impact of all the factors on the accuracy, cases were divided into two subcategories based on percentage error, with ±10% as a threshold. The accuracy of Hadlock-4 formula was compared with the two Indian population-based formulas, Hiwale-1 and Hiwale-2.
In total, 184 cases were included in the study. It was observed that the systematic error in weight estimation was significantly less in the male fetuses (8.45 ± 9.34%) in comparison to the female fetuses (11.71 ± 10.34%). The combined impact of all the factors on the accuracy was found to be nonsignificant by the multivariate analysis. The Hiwale-1 (-0.59 ± 8.75%) and Hiwale-2 (-0.65 ± 8.7%) formulas had statistically significant less errors compared to the Hadlock-4 formula (11.67 ± 7.95%).
All the studied clinical factors were found to have a limited impact on the overall accuracy of fetal weight estimation. However, the formula selection was found to have a significant impact on the accuracy, with the native population-based formulas being significantly more accurate.
本研究的主要目的是探讨产妇年龄、产次、孕周、胎儿性别、妊娠期糖尿病和妊娠期高血压对基于超声检查的胎儿体重估计准确性的影响。次要目的是找出公式选择对胎儿体重估计准确性的影响。
纳入标准为单胎活产妊娠且最后一次超声检查至分娩间隔≤7天。使用Hadlock-4公式估计胎儿体重。为研究所有因素对准确性的综合影响，根据百分比误差将病例分为两个亚组，以±10%为阈值。将Hadlock-4公式的准确性与两个基于印度人群的公式Hiwale-1和Hiwale-2进行比较。
本研究共纳入184例病例。观察到，与女胎（11.71±10.34%）相比，男胎体重估计的系统误差（8.45±9.34%）显著更小。多因素分析发现所有因素对准确性的综合影响不显著。与Hadlock-4公式（11.67±7.95%）相比，Hiwale-1公式（-0.59±8.75%）和Hiwale-2公式（-0.65±8.7%）的误差在统计学上显著更小。
所有研究的临床因素对胎儿体重估计的总体准确性影响有限。然而，发现公式选择对准确性有显著影响，基于本地人群的公式明显更准确。
