Zhang Xiao-Rui, Li Ting-Na, Ren Yuan-Yuan, Zeng Yi-Jia, Lv Hong-Yang, Wang Jin, Huang Qin-Wan
College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Pharmacol. 2020 Sep 25;11:583651. doi: 10.3389/fphar.2020.583651. eCollection 2020.
Aromatic Chinese herbs have been used to prevent plagues since ancient times. Traditional Chinese medicine has unique advantages in the prevention and treatment of epidemic diseases. According to the traditional Chinese medicine treatment plan in the National COVID-19 Diagnosis and Treatment Plan (Trial Seventh Edition) of the National Health Commission, Chinese patent medicines or prescriptions rich in aromatic Chinese herbs are selected for prevention and treatment during the period of medical observation, clinical treatment, and recovery of confirmed COVID-19 patients. Some local health committees or traditional Chinese medicine administrations recommend a variety of other ways of using traditional aromatic Chinese herbs to prevent and cure COVID-19. These involve external fumigation, use of moxibustion, and wearing of sachet. The efficacy of aromatic Chinese herbs plays a decisive role in the prevention and treatment of COVID-19. The unique properties, chemical composition, and mechanism of action of aromatic Chinese herbs are worthy of extensive and in-depth experimental and clinical research. The findings are expected to provide a reference for follow-up treatment of novel coronavirus and the development of corresponding drugs. In 2003, Dayuan-Yin produced excellent results in the treatment of the SARS virus. Individually, 112 confirmed cases were administered this drug between January and April 2003, and more than 93.7% of the patients showed noticeable mitigation of the symptoms, as well as recovery. Dayuan-Yin also was selected as one of the nationally recommended prescriptions for the COVID-19. Based on the national recommendation of Dayuan-Yin prescription, this review discusses the role of volatile components in the prevention and treatment of COVID-19, and speculates the possible mechanism of action, so as to provide a basis for the prevention and treatment of COVID-19.
芳香类中药自古以来就被用于预防瘟疫。中医在疫病防治方面具有独特优势。根据国家卫生健康委《新型冠状病毒肺炎诊疗方案（试行第七版）》中的中医治疗方案，在新冠肺炎确诊患者的医学观察期、临床治疗期及康复期，选用富含芳香类中药的中成药或方剂进行防治。一些地方卫生健康委或中医药管理部门还推荐了多种运用传统芳香类中药防治新冠肺炎的其他方法，包括熏香、艾灸、佩戴香囊等。芳香类中药的功效在新冠肺炎防治中起决定性作用。其独特的性质、化学成分及作用机制值得进行广泛深入的实验和临床研究。研究结果有望为新型冠状病毒后续治疗及相应药物研发提供参考。2003年，大元饮在治疗非典病毒方面取得了良好效果。2003年1月至4月间，112例确诊病例单独使用了该药物，超过93.7%的患者症状明显缓解并康复。大元饮还被选为新冠肺炎全国推荐方剂之一。基于大元饮方剂的全国推荐，本综述探讨了挥发性成分在新冠肺炎防治中的作用，并推测其可能的作用机制，为新冠肺炎防治提供依据。
