Wu Jinlong, Ma Yudan, Ren Zhanbing
Department of Physical Education, Shenzhen University, Shenzhen, China.
Jilin Institute of Sport Science, Changchun, China.
Front Psychol. 2020 Sep 25;11:1811. doi: 10.3389/fpsyg.2020.01811. eCollection 2020.
To evaluate the impact of virtual reality (VR) technology on the cognitive functions (overall cognitive ability, executive function, short-term memory, and long-term memory) of people with mild cognitive impairment (MCI). All major databases, including Web of Science, PubMed, Scopus, Proquest, WanFang, and CNKI, were searched to identify all relevant studies published in English or Chinese since October 28th, 2019. Two researchers independently conducted document retrieval, study selection, data extraction, and methodological quality evaluation. 15 randomized controlled trials were analyzed ( = 612 people with MCI), with the methodological quality evaluation score ranging from 5 to 7 points. A random effects model was selected to combine effect sizes. The result of the meta-analysis indicates that VR significantly enhanced MCI patients' overall cognitive ability (SMD = 0.869, 95% confidence interval [CI] = 0.330-1.407, = 0.002, = 86.822, = 537) and executive function (SMD = 1.083, 95%, 95%CI = 00.134-2.031, = 0.025, = 93.748, = 220). The meta-analysis indicated that after VR training, effects on short-term memory (SMD = 0.488, 95%CI = -0.108-1.084, = 0.109, = 62.354, = 131) and long-term memory (SMD = 0.335, 95%CI = -1.194-0.863, = 0.0.214, = 58.868, = 152) were not statistically significant. The present meta-analysis verifies the potential rehabilitative effects of VR technology for mild cognitive impairment.
评估虚拟现实（VR）技术对轻度认知障碍（MCI）患者认知功能（整体认知能力、执行功能、短期记忆和长期记忆）的影响。检索了所有主要数据库，包括Web of Science、PubMed、Scopus、Proquest、万方和知网，以识别自2019年10月28日以来发表的所有英文或中文相关研究。两名研究人员独立进行文献检索、研究选择、数据提取和方法学质量评估。分析了15项随机对照试验（n = 612例MCI患者），方法学质量评估得分在5至7分之间。选择随机效应模型合并效应量。荟萃分析结果表明，VR显著提高了MCI患者的整体认知能力（标准化均数差[SMD]=0.869，95%置信区间[CI]=0.330 - 1.407，P = 0.002，I² = 86.822，τ² = 537）和执行功能（SMD = 1.083，95%，95%CI = 0.134 - 2.031，P = 0.025，I² = 93.748，τ² = 220）。荟萃分析表明，VR训练后，对短期记忆（SMD = 0.488，95%CI = - 0.108 - 1.084，P = 0.109，I² = 62.354，τ² = 131）和长期记忆（SMD = 0.335，95%CI = - 1.194 - 0.863，P = 0.214，I² = 58.868，τ² = 152）的影响无统计学意义。本荟萃分析验证了VR技术对轻度认知障碍的潜在康复作用。
