Lifestyle (Mind-Body Movement) Research Center, College of Sport Science, Shenzhen University, Shenzhen, China.
Exercise & Memory Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, Oxford, Mississippi.
Arch Phys Med Rehabil. 2019 Aug;100(8):1556-1573. doi: 10.1016/j.apmr.2019.03.009. Epub 2019 Apr 12.
To objectively evaluate the most common forms of mind-body exercise (MBE) (tai chi, yoga, qigong) on cognitive function among people with mild cognitive impairment (MCI).
We searched 6 electronic databases (Scopus, PubMed, PsycINFO, WanFang, Web of Science, CNKI) from inception until September 2018.
Nine randomized controlled trials and 3 nonrandomized controlled trials were included for meta-analysis.
Two researchers independently performed the literature searches, study selection, data extraction, and methodological quality assessment using the revised Physiotherapy Evidence Database (PEDro) scale.
The pooled effect size (standardized mean difference [SMD]) was calculated while random-effect model was selected. Overall results of the meta-analysis (N=1298 people with MCI) indicated that MBE significantly improved attention (SMD=0.39, 95% confidence interval [CI] 0.07-0.71, P=.02, I=31.6%, n=245), short-term memory (SMD=0.74, 95% CI 0.57-0.90, P<.001, I=0%, n=861), executive function (SMD=-0.42, 95% CI -0.63 to -0.21, P<.001, I=38.54%, n=701), visual-spatial/executive function (SMD=0.35, 95% CI 0.07-0.64, P<.05, I=0%, n=285), and global cognitive function (SMD=0.36, 95% CI 0.2-0.52, P<.001, I=15.12%, n=902). However, the significant positive effect on cognitive processing speed was not observed following MBE interventions (SMD=0.31, 95% CI -0.01 to 0.63, P=.054, I=28.66%, n=233).
Study findings of this meta-analysis suggest that MBE have the potential to improve various cognitive functions in people with MCI.
客观评估轻度认知障碍（MCI）人群中最常见的身心锻炼（MBE）形式（太极、瑜伽、气功）对认知功能的影响。
我们从建库起至 2018 年 9 月，在 6 个电子数据库（Scopus、PubMed、PsycINFO、万方、Web of Science、中国知网）中进行了检索。
纳入 9 项随机对照试验和 3 项非随机对照试验进行荟萃分析。
两名研究人员独立进行文献检索、研究选择、数据提取和方法学质量评估，使用修订后的物理治疗证据数据库（PEDro）量表。
荟萃分析的总结果（N=1298 例 MCI 患者）表明，MBE 可显著改善注意力（SMD=0.39，95%置信区间[CI] 0.07-0.71，P=.02，I=31.6%，n=245）、短期记忆（SMD=0.74，95%CI 0.57-0.90，P<.001，I=0%，n=861）、执行功能（SMD=-0.42，95%CI-0.63 至-0.21，P<.001，I=38.54%，n=701）、视觉空间/执行功能（SMD=0.35，95%CI 0.07-0.64，P<.05，I=0%，n=285）和整体认知功能（SMD=0.36，95%CI 0.2-0.52，P<.001，I=15.12%，n=902）。然而，MBE 干预后并未观察到认知加工速度的显著正向影响（SMD=0.31，95%CI-0.01 至 0.63，P=.054，I=28.66%，n=233）。
这项荟萃分析的研究结果表明，MBE 有可能改善 MCI 人群的各种认知功能。
