Suppr超能文献

新型冠状病毒肺炎相关凝血病:尽管进行了抗凝治疗仍发生血栓形成的病例报告

COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation.

作者信息

Hussain Habiba, Sehring Matthew, Aulakh Bhagat Singh

机构信息

Department of Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.

Department of Pulmonary & Critical Care Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.

出版信息

Case Rep Crit Care. 2020 Oct 17;2020:8876932. doi: 10.1155/2020/8876932. eCollection 2020.

Abstract

The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的冠状病毒病(COVID-19)大流行已导致巨大的发病率和死亡率。各种炎症标志物已被监测并被认为与疾病预后相关。所涉及的合并症的主要来源之一是感染同时发生血栓形成。考虑到这种促血栓形成现象,COVID-19相关凝血病(CAC)一直是应对这种感染的讨论焦点。关于血栓预防剂量和治疗性抗凝的管理指南仍存在模糊性。我们报告一例严重SARS-CoV-2感染病例,尽管进行了治疗性抗凝,但仍并发血栓形成,导致重症监护病房和住院时间延长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3097/7573660/c9bde330a55d/CRICC2020-8876932.001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验