DiLizia E Matthew, Ahdoot Michael, Daneshvar Michael, Gomella Patrick T, Yerram Nitin K, Pinto Peter A
Department of Urology, MedStar Georgetown University Hospital, Washington, DC, USA.
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Urol Case Rep. 2020 Oct 8;34:101445. doi: 10.1016/j.eucr.2020.101445. eCollection 2021 Jan.
Definitive treatment for local prostate cancer recurrence remains controversial. Early recurrences are often from positive surgical margins or nodal metastases, however other explanations should be considered. We present a case of a 79 year-old male with localized prostate cancer and early biochemical persistence after margin-negative robotic-assisted radical prostatectomy. Workup demonstrated a 0.9 cm rectal mass without nodal or distant metastasis, and biopsy revealed prostate adenocarcinoma. A subsequent transanal excision was performed. Post-operatively, his PSA dropped to 0.02 ng/mL. We present a rare case of prostate adenocarcinoma seeding after transrectal prostate biopsy and a review of the literature.
局部前列腺癌复发的确定性治疗仍存在争议。早期复发通常源于手术切缘阳性或淋巴结转移,不过也应考虑其他原因。我们报告一例79岁男性,患有局限性前列腺癌,在切缘阴性的机器人辅助根治性前列腺切除术后出现早期生化复发。检查发现一个0.9厘米的直肠肿物,无淋巴结或远处转移,活检显示为前列腺腺癌。随后进行了经肛门切除术。术后,他的前列腺特异性抗原(PSA)降至0.02 ng/mL。我们报告一例经直肠前列腺活检后前列腺腺癌种植的罕见病例并对文献进行综述。