Deepthi R, Bilichodmath Shivaprasad
Department of Periodontology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.
Contemp Clin Dent. 2020 Apr-Jun;11(2):108-115. doi: 10.4103/ccd.ccd_79_19. Epub 2020 Aug 7.
Gingival and periodontal diseases constitute a major distress in the field of dentistry. The greater part of the contributing and etiologic factors are diminished or treated with all forms of ozone. Ozone which is well known for its antimicrobial and tissue regenerative properties is indicated in all the stages of gingival and periodontal diseases. The aim of this study was to review literature on the effects of ozone as an adjunct to mechanical therapy in periodontitis patients. A search of literature was conducted to identify articles of ozone therapy in periodontitis published during the period from January 1, 2010, to July 30, 2018. PubMed, Medline, Embase, Cochrane, and Google Scholar search and hand searching of journals were conducted to identify relevant articles. The search strategy employed both dental subject headings and free-text terms. Out of a total of 123 studies that fit the initial inclusion criteria, 117 studies were further excluded. Only six studies were included in the meta-analyses. A high level of heterogeneity in the selected studies was found as demonstrated by Q-value of 10.241 and value of 80.49%. However, the funnel plots showed symmetrical shape, with prevalence studies indicating absence of publication bias. Ozone therapy can be used effectively as an adjunct to scaling and root planing in the treatment of periodontitis.
牙龈疾病和牙周疾病是牙科领域的主要困扰。大部分促成因素和病因都可以通过各种形式的臭氧来减少或治疗。臭氧以其抗菌和组织再生特性而闻名，适用于牙龈疾病和牙周疾病的各个阶段。本研究的目的是回顾关于臭氧作为牙周炎患者机械治疗辅助手段效果的文献。通过检索文献来识别2010年1月1日至2018年7月30日期间发表的有关臭氧治疗牙周炎的文章。检索了PubMed、Medline、Embase、Cochrane以及谷歌学术，并对期刊进行手工检索以识别相关文章。检索策略同时使用了牙科主题词和自由文本术语。在符合初始纳入标准的总共123项研究中，又排除了117项研究。只有六项研究被纳入荟萃分析。所选研究存在高度异质性，Q值为10.241，I²值为80.49%。然而，漏斗图显示出对称形状，患病率研究表明不存在发表偏倚。臭氧治疗可有效用作牙周炎治疗中龈下刮治和根面平整的辅助手段。
