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臭氧疗法在减轻牙周病方面的疗效

Efficacy Ozone Therapy in Reducing Periodontal Disease.

作者信息

Tetè Giulia, D'Amicantonio Teresa, Polizzi Elisabetta

机构信息

Vita-Salute San Raffaele University, Dental School Department of Dentistry, IRCCS San Raffaele Hospital, Via Olgettina 48, 20132 Milan, Italy.

Center for Oral Hygiene and Prevention, Vita-Salute San Raffaele University, Dental School Department of Dentistry, IRCCS San Raffaele Hospital, Via Olgettina 48, 20132 Milan, Italy.

出版信息

Materials (Basel). 2023 Mar 16;16(6):2375. doi: 10.3390/ma16062375.

DOI:10.3390/ma16062375
PMID:36984255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10056049/
Abstract

The aim of this study is to highlight the properties of ozone as an aid to non-surgical therapy compared to non-surgical therapy alone. This study included thirty Caucasian patients (eighteen women and twelve men) aged between 35 and 65, recruited at the Oral Hygiene and Prevention Center of the Dental Clinic of the Vita-Salute San Raffaele University, at the San Raffaele hospital in Milan. The periodontal probing was recorded with a PC-PUNC 15 manual probe (Hu Friedy) at time 0; the scaling and root planing session was performed at T1 with or without the aid of ozone therapy, and then, the patients were re-evaluated at one month (T2), three months (T3), and six months (T4). The results obtained show that there are not statistically significant differences in terms of reduction in clinical periodontal indices such as plaque, bleeding, and pocket depth between the two groups. Therefore, treatment with ozoral gel would not seem to improve non-surgical periodontal therapy alone. However, clinical periodontal indices significantly improved in patients treated with non-surgical therapy and ozone gel. From this point of view, ozone gel can be used as an aid to non-surgical therapy due to its excellent characteristics, in particular, its powerful virucidal action.

摘要

本研究的目的是突出臭氧作为辅助非手术治疗手段相较于单纯非手术治疗的特性。本研究纳入了30名年龄在35至65岁之间的白种人患者(18名女性和12名男性),这些患者是在米兰圣拉斐尔医院的维塔-萨尔ute圣拉斐尔大学牙科诊所的口腔卫生与预防中心招募的。在时间0时,使用PC-PUNC 15手动探针(Hu Friedy)记录牙周探诊情况;在T1时进行龈上洁治和根面平整操作,操作过程中一组使用臭氧治疗,另一组不使用,然后在1个月(T2)、3个月(T3)和6个月(T4)时对患者进行重新评估。所获得的结果表明,两组在菌斑、出血和牙周袋深度等临床牙周指标的降低方面没有统计学上的显著差异。因此,单独使用臭氧凝胶治疗似乎并不能改善非手术牙周治疗效果。然而,接受非手术治疗和臭氧凝胶治疗的患者临床牙周指标有显著改善。从这一角度来看,由于臭氧凝胶具有出色的特性,特别是其强大的杀病毒作用,它可以作为非手术治疗的辅助手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/c2da1175792a/materials-16-02375-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/7821dcdac6b6/materials-16-02375-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/095fc489d0ba/materials-16-02375-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/c2da1175792a/materials-16-02375-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/7821dcdac6b6/materials-16-02375-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/095fc489d0ba/materials-16-02375-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f64/10056049/c2da1175792a/materials-16-02375-g003.jpg

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Influence of epigenetics on periodontitis and peri-implantitis pathogenesis.表观遗传学对牙周炎和种植体周围炎发病机制的影响。
Periodontol 2000. 2022 Oct;90(1):125-137. doi: 10.1111/prd.12453. Epub 2022 Aug 1.
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Risk factors for periodontitis & peri-implantitis.
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Int J Mol Sci. 2024 Jun 29;25(13):7217. doi: 10.3390/ijms25137217.
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Periodontal and Peri-Implant Diagnosis: Current Evidence and Future Directions.牙周和种植体周围疾病的诊断:当前证据与未来方向。
Diagnostics (Basel). 2024 Jan 25;14(3):256. doi: 10.3390/diagnostics14030256.
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Evaluation of the healing potential of short-term ozone therapy for the treatment of diabetic foot ulcers.评价短期臭氧疗法治疗糖尿病足溃疡的愈合潜力。
Front Endocrinol (Lausanne). 2024 Jan 15;14:1304034. doi: 10.3389/fendo.2023.1304034. eCollection 2023.
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Dent J (Basel). 2023 Aug 7;11(8):187. doi: 10.3390/dj11080187.
牙周炎和种植体周围炎的危险因素。
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