Yılmaz Selçuk, Algan Serdar, Gursoy Hare, Noyan Ulku, Kuru Bahar Eren, Kadir Tanju
Faculty of Dentistry, Department of Periodontology, Yeditepe University, Istanbul, Turkey.
Photomed Laser Surg. 2013 Jun;31(6):293-8. doi: 10.1089/pho.2012.3379.
The aim of this study was to evaluate the clinical and microbiological results of treatment with the Er:YAG laser and topical gaseous ozone application as adjuncts to initial periodontal therapy in chronic periodontitis (CP) patients.
Although many studies have evaluated the effectiveness of the Er:YAG laser as an adjunct to initial periodontal therapy, few studies have focused on the use of gaseous ozone as an adjunct.
Thirty patients with CP were randomly divided into three parallel groups, each composed of 10 individuals with at least four teeth having at least one approximal site with a probing depth (PD) of ≥5 mm and a sulcus bleeding index (SBI) ≥2 in each quadrant. Groups of patients received: (1) Scaling and root planing (SRP)+Er:YAG laser; (2) SRP+topical gaseous ozone; or (3) SRP alone. The microbiological and clinical parameters were monitored at day 0 and day 90.
At the end of the observation period, statistically significant improvements in clinical parameters were observed within each group. Parallel to the clinical changes, all treatments reduced the number of total bacteria and the proportion of obligately anaerobic microorganisms. Although intergroup comparisons of microbiological parameters showed no significant differences, clinical findings, including attachment gain and PD reduction, were found to be statistically significant in favor of the SRP+Er:YAG laser group.
Although statistically nonsignificant, the fact that the obligate anaerobic change was mostly observed in the SRP+Er:YAG laser group, and a similar decrease was noted in the SRP+topical gaseous ozone group, shows that ozone has an antimicrobial effect equivalent to that of the Er:YAG laser.
本研究旨在评估铒激光联合局部应用气态臭氧辅助治疗慢性牙周炎（CP）患者初始牙周治疗的临床和微生物学效果。
尽管许多研究评估了铒激光辅助初始牙周治疗的有效性，但很少有研究关注气态臭氧作为辅助治疗的应用。
30例CP患者被随机分为三个平行组，每组10人，每人至少有四颗牙齿，每个象限至少有一个邻面探诊深度（PD）≥5mm且龈沟出血指数（SBI）≥2的部位。患者分组接受：（1）龈上洁治和根面平整（SRP）+铒激光；（2）SRP+局部气态臭氧；或（3）仅SRP。在第0天和第90天监测微生物学和临床参数。
在观察期结束时，每组的临床参数均有统计学上的显著改善。与临床变化同时，所有治疗均减少了总细菌数量和专性厌氧微生物的比例。尽管微生物学参数的组间比较无显著差异，但包括附着增加和PD减少在内的临床结果在SRP+铒激光组中具有统计学显著性优势。
虽然在统计学上无显著差异，但专性厌氧变化主要在SRP+铒激光组中观察到，且在SRP+局部气态臭氧组中也有类似下降，这一事实表明臭氧具有与铒激光相当的抗菌作用。
