Apriani Anie, Widyarman Armelia Sari, Budiyanti E Arlia, Roeslan Boedi Oetomo
Post Graduate Student Faculty of Dentistry Trisakti University, Jakarta, Indonesia.
Department of Pediatric Dentistry, Maranatha Christian University, Bandung, Indonesia.
Contemp Clin Dent. 2020 Apr-Jun;11(2):126-130. doi: 10.4103/ccd.ccd_167_20. Epub 2020 Aug 7.
Caries is a disease affecting the hard tissue of the tooth wherein the demineralization process caused by decreases saliva pH faster than the remineralization process can maintain it. Topical fluoridation, such as fluoride varnish and casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) is the most common preventive therapy for the disease.
The aim of this study is to assess the difference between fluoride varnish and CPP-ACP in reducing saliva pH and caries activity.
This is an experimental study with a sample population of 60 children (aged 8-9 years old), divided into two groups of 30. Group 1 was treated with fluoride varnish, Group 2 with CPP-ACP. A -test was used to measure the effects of the different treatments.
The result showed that the average difference in saliva pH before and after application was -0.12933 in Group 1 and -0.14033 in Group 2 ( = 0.256). The average difference in caries activity before and after application was 3.189 log colony-forming units (CFUs)/mL in Group 1 and 2.237 log CFUs/mL in Group 2 ( = 0.275).
The most effective treatment for increasing saliva pH and reducing caries activity can be achieved by using the varnish for 1 month. However, there is no difference between fluoride varnish and CPP-ACP with regard to altering saliva pH and reducing caries activity statistically. Future study is needed to explore this result.
龋齿是一种影响牙齿硬组织的疾病，其中由唾液pH值下降引起的脱矿过程比再矿化过程维持其平衡的速度更快。局部用氟，如氟化漆和酪蛋白磷酸肽 - 无定形磷酸钙（CPP - ACP）是该疾病最常见的预防疗法。
本研究的目的是评估氟化漆和CPP - ACP在降低唾液pH值和龋齿活性方面的差异。
这是一项实验研究，样本为60名儿童（8 - 9岁），分为两组，每组30人。第1组用氟化漆治疗，第2组用CPP - ACP治疗。采用t检验来测量不同治疗方法的效果。
结果显示，第1组涂抹前后唾液pH值的平均差异为 - 0.12933，第2组为 - 0.14033（P = 0.256）。第1组涂抹前后龋齿活性的平均差异为3.189 log菌落形成单位（CFU）/mL，第2组为2.237 log CFU/mL（P = 0.275）。
使用氟化漆1个月可最有效地提高唾液pH值并降低龋齿活性。然而，在改变唾液pH值和降低龋齿活性方面，氟化漆和CPP - ACP在统计学上没有差异。需要进一步的研究来探究这一结果。
