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伴有钙化的成釉细胞癌:下颌骨罕见病例报告及文献综述

Ameloblastic Carcinoma with Calcification: A Rare Case Report in the Mandible and Literature Review.

作者信息

Khoozestani Neda Kardouni, Mosavat Farzaneh, Shirkhoda Mohammad, Azar Ramtin

机构信息

Departments of Oral and Maxillofacial Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.

Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Dent. 2020 Oct 13;2020:4216489. doi: 10.1155/2020/4216489. eCollection 2020.

Abstract

Ameloblastic carcinoma (AC) is a scarce malignant tumor which is more prevalent in the mandible than the maxilla. It occurs in a wide range of age groups, and there is a sex predilection in males. AC shows specific microscopic features and requires more aggressive surgical treatment plans in comparison with conventional ameloblastoma. Radiographically, AC resembles ameloblastoma except that it rarely represents focal mineralized materials, seemingly reflecting dystrophic calcification. This characteristic is uncommon in typical ameloblastomas, and only few cases reported with such opacities and mineralized materials. Due to this rare radiographic and microscopic presentation, an accurate diagnosis could be challenging, and pathologists should consider a combination of benign and malignant odontogenic tumors occurring in jaws.

摘要

成釉细胞癌(AC)是一种罕见的恶性肿瘤,在下颌骨比在上颌骨更常见。它发生于广泛的年龄组,男性有性别偏好。与传统成釉细胞瘤相比,AC具有特定的微观特征,需要更积极的手术治疗方案。在影像学上,AC类似于成釉细胞瘤,只是它很少出现局灶性矿化物质,这似乎反映了营养不良性钙化。这种特征在典型成釉细胞瘤中并不常见,只有少数病例报告有这种不透光区和矿化物质。由于这种罕见的影像学和微观表现,准确诊断可能具有挑战性,病理学家应考虑颌骨中发生的良性和恶性牙源性肿瘤的组合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5999/7578728/b1de0d984a3d/CRID2020-4216489.001.jpg

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