Conte Juliette, Yoo Michael J, Larson Neil P
Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, San Antonio, USA.
Cureus. 2020 Sep 22;12(9):e10599. doi: 10.7759/cureus.10599.
Takotsubo cardiomyopathy (TCOM) is a syndrome characterized by acute systolic dysfunction that can mimic acute coronary syndrome (ACS), usually incited by physical or emotional stress. However, acute neurological dysfunction, including seizures, has been recently described as an additional risk factor for the development of TCOM. This specific case report reviews the pathophysiology of TCOM and its management. We emphasize that providers should maintain a high index of suspicion for TCOM after acute neurologic dysfunction in patients with chest pain or hemodynamic instability, while also initiating proper investigation for ACS. Although classically thought of as a transient process, recent data show that both in-hospital and post-hospital morbidity and mortality related to this condition remain concerning.
应激性心肌病（TCOM）是一种以急性收缩功能障碍为特征的综合征，可类似于急性冠脉综合征（ACS），通常由身体或情绪应激诱发。然而，急性神经功能障碍，包括癫痫发作，最近被描述为TCOM发生的另一个危险因素。本病例报告回顾了TCOM的病理生理学及其管理。我们强调，对于胸痛或血流动力学不稳定的患者，在急性神经功能障碍后，医护人员应高度怀疑TCOM，同时也要对ACS展开适当检查。尽管传统上认为这是一个短暂的过程，但最近的数据显示，与该病症相关的院内和院后发病率及死亡率仍然令人担忧。
