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本文引用的文献

1
A Review of the Presentation of Overdiagnosis in Cancer Screening Patient Decision Aids.癌症筛查患者决策辅助工具中过度诊断呈现情况的综述
MDM Policy Pract. 2019 Nov 6;4(2):2381468319881447. doi: 10.1177/2381468319881447. eCollection 2019 Jul-Dec.
2
Estimating the magnitude of cancer overdiagnosis in Australia.估算澳大利亚癌症过度诊断的程度。
Med J Aust. 2020 Mar;212(4):163-168. doi: 10.5694/mja2.50455. Epub 2019 Dec 19.
3
Defining and Evaluating Overdiagnosis in Mental Health: A Meta-Research Review.定义和评估心理健康中的过度诊断:元研究综述。
Psychother Psychosom. 2019;88(4):193-202. doi: 10.1159/000501647. Epub 2019 Jul 24.
4
Cancer overdiagnosis: a biological challenge and clinical dilemma.癌症过度诊断:生物学挑战与临床困境
Nat Rev Cancer. 2019 Jun;19(6):349-358. doi: 10.1038/s41568-019-0142-8.
5
Overdiagnosis of COPD in Subjects With Unobstructed Spirometry: A BOLD Analysis.肺通气功能正常的 COPD 患者过度诊断:一项 BOLD 分析。
Chest. 2019 Aug;156(2):277-288. doi: 10.1016/j.chest.2019.01.015. Epub 2019 Jan 31.
6
Screening and overdiagnosis: public health implications.筛查与过度诊断:对公共卫生的影响
Public Health Rev. 2015 Nov 5;36:8. doi: 10.1186/s40985-015-0012-1. eCollection 2015.
7
Overdiagnosis: what it is and what it isn't.过度诊断:是什么以及不是什么。
BMJ Evid Based Med. 2018 Feb;23(1):1-3. doi: 10.1136/ebmed-2017-110886.
8
Gestational Diabetes Mellitus: Why the Controversy?妊娠期糖尿病:为何存在争议?
Clin Chem. 2018 Mar;64(3):431-438. doi: 10.1373/clinchem.2016.266577. Epub 2017 Oct 11.
9
Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis.丹麦的乳腺癌筛查:一项关于肿瘤大小和过度诊断的队列研究。
Ann Intern Med. 2017 Mar 7;166(5):313-323. doi: 10.7326/M16-0270. Epub 2017 Jan 10.
10
Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness.乳腺癌肿瘤大小、过度诊断与乳腺 X 线筛查效果
N Engl J Med. 2016 Oct 13;375(15):1438-1447. doi: 10.1056/NEJMoa1600249.

过度诊断与过度治疗;如何应对过度医疗。

Overdiagnosis and overtreatment; how to deal with too much medicine.

作者信息

Gupta Puneeta, Gupta Meeta, Koul Neeraj

机构信息

Department of Medicine, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, J&K, India.

Department of Obstetrics and Gynaecology, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, J&K, India.

出版信息

J Family Med Prim Care. 2020 Aug 25;9(8):3815-3819. doi: 10.4103/jfmpc.jfmpc_433_20. eCollection 2020 Aug.

DOI:10.4103/jfmpc.jfmpc_433_20
PMID:33110773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7586591/
Abstract

The past few decades have seen medical science making rapid strides in the field of diagnostic technologies, thus making it possible to detect some conditions at a very early stage. An unwanted effect of these developments is overdiagnosis which occurs when a true abnormality is discovered, but detection of that abnormality and its treatment does not benefit the patient. Overdiagnosis is encountered as a result cancer screening, in genetic diseases and in some chronic conditions when disease definition is broadened. There is urgent need of development of evidence based decision-making tools for clinicians which will help patients understand the benefits and harms of different screening and treatment methods. And the treating physician has to play a important role to convince the patient that watchful waiting, for some of the lesions may be the best option available in some circumstances.

摘要

在过去几十年里,医学科学在诊断技术领域取得了飞速进展,从而能够在非常早期阶段检测出某些病症。这些发展带来的一个不良影响是过度诊断,即当发现真正的异常情况,但对该异常的检测及其治疗对患者并无益处时就会出现过度诊断。在癌症筛查、遗传疾病以及一些慢性病中,当疾病定义扩大时就会出现过度诊断。迫切需要为临床医生开发基于证据的决策工具,这将有助于患者理解不同筛查和治疗方法的益处与危害。而且主治医生必须发挥重要作用,使患者相信,对于某些病变,在某些情况下观察等待可能是最佳选择。