Low-cost air quality sensors can help increase spatial and temporal resolution of air pollution exposure measurements. These sensors, however, most often produce data of lower accuracy than higher-end instruments. In this study, we investigated linear and random forest models to correct PM measurements from the Denver Department of Public Health and Environment (DDPHE)'s network of low-cost sensors against measurements from co-located U.S. Environmental Protection Agency Federal Equivalence Method (FEM) monitors. Our training set included data from five DDPHE sensors from August 2018 through May 2019. Our testing set included data from two newly deployed DDPHE sensors from September 2019 through mid-December 2019. In addition to PM, temperature, and relative humidity from the low-cost sensors, we explored using additional temporal and spatial variables to capture unexplained variability in sensor measurements. We evaluated results using spatial and temporal cross-validation techniques. For the long-term dataset, a random forest model with all time-varying covariates and length of arterial roads within 500 m was the most accurate (testing RMSE = 2.9 μg/m and R = 0.75; leave-one-location-out (LOLO)-validation metrics on the training set: RMSE = 2.2 μg/m and R = 0.93). For on-the-fly correction, we found that a multiple linear regression model using the past eight weeks of low-cost sensor PM, temperature, and humidity data plus a near-highway indicator predicted each new week of data best (testing RMSE = 3.1 μg/m and R = 0.78; LOLO-validation metrics on the training set: RMSE = 2.3 μg/m and R = 0.90). The statistical methods detailed here will be used to correct low-cost sensor measurements to better understand PM pollution within the city of Denver. This work can also guide similar implementations in other municipalities by highlighting the improved accuracy from inclusion of variables other than temperature and relative humidity to improve accuracy of low-cost sensor PM data.