白色念珠菌芽生孢子的吞噬作用对大鼠多形核白细胞碱性磷酸酶水平的影响。
The effect of phagocytosis of Candida albicans blastospores on alkaline phosphatase levels in rat polymorphonuclear leucocytes.
作者信息
Lu W H, Williams D M
机构信息
Department of Oral Pathology, London Hospital Medical College, UK.
出版信息
Histochem J. 1987 Jun-Jul;19(6-7):333-6. doi: 10.1007/BF01680449.
The phagocytic function of young polymorphonuclear leucocytes with high levels of leucocyte alkaline phosphatase, which are present in the peripheral blood during an inflammatory response, was compared with that of normal polymorphonuclear leucocytes. Candida albicans blastospores were used as phagocytic targets. The phagocytic index of polymorphonuclear leucocytes with low levels of leucocyte alkaline phosphatase was higher than that of cells with high levels of enzyme. Monitoring of leucocyte alkaline phosphatase levels with increasing times of incubation of leucocytes with the blastospores showed a progressive decline in the level of the enzyme. Thus loss of the enzyme is linked to the phagocytic function, although the mechanism of this dynamic process is unclear.
将炎症反应期间外周血中存在的、具有高水平白细胞碱性磷酸酶的年轻多形核白细胞的吞噬功能，与正常多形核白细胞的吞噬功能进行了比较。白色念珠菌芽生孢子用作吞噬靶标。白细胞碱性磷酸酶水平低的多形核白细胞的吞噬指数高于酶水平高的细胞。随着白细胞与芽生孢子孵育时间的增加，监测白细胞碱性磷酸酶水平，结果显示该酶的水平逐渐下降。因此，尽管这一动态过程的机制尚不清楚，但酶的丧失与吞噬功能有关。
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