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2017 年美国阿片类药物使用障碍和致命阿片类药物过量的经济负担。

The economic burden of opioid use disorder and fatal opioid overdose in the United States, 2017.

机构信息

Division of Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Division of Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.

出版信息

Drug Alcohol Depend. 2021 Jan 1;218:108350. doi: 10.1016/j.drugalcdep.2020.108350. Epub 2020 Oct 27.

Abstract

BACKGROUND

The United States (U.S.) is experiencing an ongoing opioid crisis. Economic burden estimates that describe the impact of the crisis are needed when considering federal and state resources devoted to addressing overdoses. In this study, we estimate the societal costs for opioid use disorder and fatal overdose from all opioids in 2017.

METHODS

We estimated costs of fatal overdose from all opioids and opioid use disorder based on the incidence of overdose deaths and the prevalence of past-year opioid use disorder for 2017. Incidence of fatal opioid overdose was obtained from the National Vital Statistics System; prevalence of past-year opioid use disorder was estimated from the National Survey of Drug Use and Health. Costs were estimated for health care, criminal justice and lost productivity. Costs for the reduced quality of life for opioid use disorder and life lost due to fatal opioid overdose were valued using U.S. Department of Health and Human Services guidelines for valuing reductions in morbidity and mortality.

RESULTS

Costs for opioid use disorder and fatal opioid overdose in 2017 were estimated to be $1.02 trillion. The majority of the economic burden is due to reduced quality of life from opioid use disorder and the value of life lost due to fatal opioid overdose.

CONCLUSIONS

These estimates can assist decision makers in understanding the magnitude of opioid use disorder and fatal overdose. Knowing the magnitude and distribution of the economic burden can inform public policy, clinical practice, research, and prevention and response activities.

摘要

背景

美国正在经历一场持续的阿片类药物危机。在考虑用于解决过量用药的联邦和州资源时,需要有描述该危机影响的经济负担估计。在这项研究中,我们估计了 2017 年所有类阿片药物导致的药物使用障碍和致命药物过量的社会成本。

方法

我们根据 2017 年药物过量死亡的发生率和过去一年药物使用障碍的流行率,估算了所有类阿片药物和药物使用障碍导致的致命药物过量的成本。致命药物过量的发生率从国家生命统计系统获得;过去一年药物使用障碍的流行率从国家药物使用与健康调查中估计。我们为医疗保健、刑事司法和生产力损失估算了成本。使用美国卫生与公众服务部关于评估发病率和死亡率降低的指南,对药物使用障碍导致的生活质量降低和致命药物过量导致的生命损失的成本进行了估值。

结果

2017 年药物使用障碍和致命药物过量的成本估计为 1.02 万亿美元。经济负担的大部分是由于药物使用障碍导致的生活质量下降和致命药物过量导致的生命损失。

结论

这些估计可以帮助决策者了解药物使用障碍和致命药物过量的严重程度。了解经济负担的规模和分布可以为公共政策、临床实践、研究以及预防和应对活动提供信息。

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