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喉内嗜酸性细胞囊腺瘤,类似于喉黏液囊肿。

Laryngeal oncocytic cystadenoma mimicking a combined laryngomucocele.

机构信息

Department of Otorhinolaryngology, Hospital da Senhora da Oliveira Guimarães, Guimaraes, Portugal

Department of Otorhinolaryngology, Hospital da Senhora da Oliveira Guimarães, Guimaraes, Portugal.

出版信息

BMJ Case Rep. 2020 Oct 29;13(10):e236866. doi: 10.1136/bcr-2020-236866.

DOI:10.1136/bcr-2020-236866
PMID:33122233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7597479/
Abstract

Laryngeal oncocytic cystadenomas are rare benign tumours lined by oncocytic epithelium and arising from the salivary glands; they usually present as a supraglottic mass. Oncocytic changes are very uncommon in the larynx and occur mainly in ventricles and false vocal cords, where seromucinous glands predominate. The authors present the case of a 62-year-old woman who reported a 6-month history of hoarseness associated with a soft and non-compressible upper left side neck swelling. Transnasal fiberoptic laryngoscopy revealed a left submucosal supraglottic mass involving the false vocal fold and the vallecula, partially obstructing the airway. CT scan showed a homogeneous isodense cystic lesion centred at the left laryngeal ventricle, with extension through the thyrohyoid membrane. The patient was successfully managed by a lateral thyrotomy approach. Histopathological examination of the specimen revealed a papillary oncocytic cystadenoma and excluded malignancy. There was no evidence of recurrence after 9 months of follow-up.

摘要

喉涎腺型嗜酸细胞瘤是一种罕见的良性肿瘤,由嗜酸细胞上皮构成,来源于涎腺;它们通常表现为会厌前间隙肿块。嗜酸细胞改变在喉部非常罕见,主要发生在室带和假声带,那里以浆液黏液腺为主。作者报告了一例 62 岁女性病例,该患者因声音嘶哑就诊,伴有 6 个月的左侧上颈部柔软且不可压缩性肿胀史。经鼻纤维喉镜检查显示左侧会厌前间隙黏膜下肿块累及假声带和杓会厌皱襞,部分阻塞气道。CT 扫描显示左喉室中心位置存在均匀等密度囊性病变,通过甲状舌骨膜延伸。患者通过外侧甲状腺切开术成功治疗。标本的组织病理学检查显示为乳头状嗜酸细胞瘤囊腺瘤,排除了恶性肿瘤。随访 9 个月后无复发证据。

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引用本文的文献

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Oncocytic Papillary Cystadenoma: A Case of a Misdiagnosed Laryngeal Mass.嗜酸性乳头状囊腺瘤:一例误诊为喉部肿物的病例
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Eur Arch Otorhinolaryngol. 2021 Sep;278(9):3381-3386. doi: 10.1007/s00405-021-06841-2. Epub 2021 Apr 28.

本文引用的文献

1
Oncocytic cyst of the larynx: a rare finding.喉嗜酸细胞囊肿:一种罕见的发现。
BMJ Case Rep. 2019 Jan 18;12(1):bcr-2018-227214. doi: 10.1136/bcr-2018-227214.
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Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience.囊状囊肿的临床特征与管理:单机构经验
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Laryngeal Cysts in Adults: Simplifying Classification and Management.成人喉囊肿:简化分类与管理
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Laryngeal oncocytic cystadenomas masquerading as laryngoceles.伪装成喉气囊肿的喉嗜酸细胞囊腺瘤
Am J Otolaryngol. 2016 Jan-Feb;37(1):17-21. doi: 10.1016/j.amjoto.2015.09.010. Epub 2015 Sep 10.
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Recurrent Warthin's tumour of the larynx.复发性喉沃辛瘤
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Squamous cell carcinoma of the larynx arising in multifocal pharyngolaryngeal oncocytic papillary cystadenoma: a case report and review of the literature.多灶性咽喉嗜酸性乳头状囊腺瘤中发生的喉鳞状细胞癌:一例报告并文献复习
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Surgical and anesthetic considerations of laryngeal saccular cyst: a case report.喉内囊肿的手术及麻醉考量:一例病例报告
J Med Case Rep. 2011 Jul 5;5:283. doi: 10.1186/1752-1947-5-283.
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Ear Nose Throat J. 2009 Jul;88(7):1003-4.
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Oncocytic cyst of the larynx: an unusual occurrence.喉嗜酸细胞囊肿:一种罕见病例。
Acta Otorhinolaryngol Ital. 2007 Aug;27(4):212-5.