Anlló Hernán, Herer Bertrand, Delignières Agathe, Bocahu Yolaine, Segundo Isabelle, Mach Alingrin Valérie, Gilbert Marion, Larue François
Clinical Hypnosis Research Team, Bligny Hospital Center, Briis-sous-Forges, France.
Watanabe Cognitive Science Laboratory, School of Fundamental Science and Engineering. Waseda University, Tokyo, Japan.
Int J Chron Obstruct Pulmon Dis. 2020 Oct 22;15:2609-2620. doi: 10.2147/COPD.S267019. eCollection 2020.
Patients with chronic obstructive pulmonary disease (COPD) are prone to dyspnea, increased respiratory rate and other anxiety-inducing symptoms. Hypnosis constitutes a complementary procedure capable of improving subjective feelings of anxiety.
Assessing the efficacy of a 15-minute hypnosis intervention for immediate improvement of anxiety in severe COPD patients.
Twenty-one participants, COPD patients (mean FEV1 < 32.3%), were randomly assigned to two individual sessions in crossover (sham and hypnosis, 24-h washout period, arms: hypnosis-sham [n=11]/sham-hypnosis [n=10]). We tracked pre- and post-intervention anxiety (STAI-6 score) as primary endpoint.
Nineteen (90.5%) participants completed the study. Anxiety diminished significantly after hypnosis (STAI-6 scores -23.8% [SD = 18.4%] hypnosis vs -3.1% [32.8%] sham; χ=8, P<0.01, Bayes Factor 5.5). Respiratory rate also decreased after hypnosis. Improvements in SpO2 and Borg exertion scores were registered after both conditions.
A 15-minute hypnosis session improved participants' anxiety and lowered respiratory rate (as opposed to sham). Improvements in anxiety were correlated with an alleviation in respiratory strain. Results imply that hypnosis can contribute to the improvement of anxiety levels and breathing mechanics in severe COPD patients.
ISRCTN10029862.
慢性阻塞性肺疾病（COPD）患者容易出现呼吸困难、呼吸频率增加及其他诱发焦虑的症状。催眠是一种能够改善主观焦虑感受的辅助手段。
评估15分钟催眠干预对重度COPD患者焦虑即刻改善的疗效。
21名COPD患者（平均第1秒用力呼气容积<32.3%）被随机交叉分配到两个单独疗程（假催眠和催眠，洗脱期24小时，分组：催眠-假催眠[n = 11]/假催眠-催眠[n = 10]）。我们将干预前后的焦虑（状态特质焦虑问卷-6评分）作为主要终点进行追踪。
19名（90.5%）参与者完成了研究。催眠后焦虑显著减轻（状态特质焦虑问卷-6评分：催眠组降低23.8%[标准差=18.4%]，假催眠组降低3.1%[32.8%]；χ=8，P<0.01，贝叶斯因子5.5）。催眠后呼吸频率也降低。两种情况后血氧饱和度（SpO2）和博格劳累评分均有改善。
15分钟的催眠疗程改善了参与者的焦虑并降低了呼吸频率（与假催眠相反）。焦虑的改善与呼吸压力的减轻相关。结果表明，催眠有助于改善重度COPD患者的焦虑水平和呼吸力学。
ISRCTN10029862。
