Department of Geriatric Dentistry, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Inquiry. 2020 Jan-Dec;57:46958020968777. doi: 10.1177/0046958020968777.
In this pilot, single-blind, randomized controlled trial, we investigated the effects of intensified oral hygiene care (IOHC) on reducing stroke-associated pneumonia (SAP) incidence. Patients admitted within 24 hours of stroke onset were recruited and randomized to receive IOHC or routine oral hygiene care. The occurrence of SAP was checked and oral swabs were obtained during the 7-day follow-up. The SAP incidence was lower, though not significantly, in the IOHC group than in the control group. IOHC successfully decreased SAP incidence among patients who were male, had higher National Institutes of Health Stroke Scale and Debris Index scores, and lower Glasgow Coma Scale and Gugging Swallowing Screen scores. Furthermore, IOHC significantly decreased the prevalence of oral suspected SAP pathogens. These results suggest that IOHC can decrease the incidence of SAP in the most vulnerable patient groups and lower the prevalence of suspected oral SAP pathogens.
在这项初步、单盲、随机对照试验中，我们研究了强化口腔卫生护理（IOHC）对降低卒中相关性肺炎（SAP）发生率的影响。招募了发病后 24 小时内入院的患者，并将其随机分为接受 IOHC 或常规口腔卫生护理的两组。在 7 天的随访期间，检查 SAP 的发生情况并采集口腔拭子。虽然 IOHC 组的 SAP 发生率较低，但无统计学意义。IOHC 成功降低了男性、NIHSS 和 Debris 指数评分较高以及 Glasgow 昏迷量表和 Gugging 吞咽屏评分较低的患者的 SAP 发生率。此外，IOHC 还显著降低了疑似 SAP 口腔病原体的流行率。这些结果表明，IOHC 可降低最脆弱患者群体的 SAP 发生率，并降低疑似 SAP 口腔病原体的流行率。
