NYU Grossman School of Medicine School of Medicine, New York, NY, USA.
Rollins School of Public Health, Emory University, Atlanta, GA, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Sleep Med. 2020 Dec;76:89-97. doi: 10.1016/j.sleep.2020.09.005. Epub 2020 Sep 14.
Suboptimal sleep, including insufficient/long sleep duration and poor sleep quality, is a risk factor for cardiovascular disease (CVD) common but there is little information among African Americans, a group with a disproportionate CVD burden. The current study examined the association between suboptimal sleep and incident CVD among African Americans.
This study included 4,522 African Americans without CVD at baseline (2000-2004) of the Jackson Heart Study (JHS). Self-reported sleep duration was defined as very short (<6 h/night), short (6 h/night), recommended (7-8 h/night), and long (≥9 h/night). Participants' self-reported sleep quality was defined as "high" and "low" quality. Suboptimal sleep was defined by low quality sleep and/or insufficient/long sleep duration. Incident CVD was a composite of incident coronary heart disease and stroke. Associations between suboptimal sleep and incident CVD were examined using Cox proportional hazards models over 15 follow-up years with adjustment for predictors of CVD risk and obstructive sleep apnea.
Sample mean age was 54 years (SD = 13), 64% female and 66% reported suboptimal sleep. Suboptimal sleep was not associated with incident CVD after covariate adjustment [HR(95% CI) = 1.18(0.97-1.46)]. Long [HR(95%CI) = 1.32(1.02-1.70)] and very short [HR(95% CI) = 1.56(1.06-2.30)] sleep duration were associated with incident CVD relative to recommended sleep duration. Low quality sleep was not associated with incident CVD (p = 0.413).
Long and very short self-reported sleep duration but not self-reported sleep quality were associated with increased hazard of incident CVD.
睡眠质量不佳（包括睡眠时间不足/过长和睡眠质量差）是心血管疾病（CVD）的一个危险因素，在人群中较为常见，但在非洲裔美国人中，这方面的信息却很少，而非洲裔美国人患 CVD 的负担不成比例。本研究旨在探讨睡眠质量不佳与非洲裔美国人 CVD 发病的关系。
这项研究纳入了 4522 名在 2000-2004 年杰克逊心脏研究（JHS）中基线时无 CVD 的非洲裔美国人。自我报告的睡眠时间定义为非常短（每晚<6 小时）、短（每晚 6 小时）、推荐（每晚 7-8 小时）和长（每晚≥9 小时）。参与者的自我报告睡眠质量定义为“高”和“低”质量。睡眠质量不佳定义为睡眠质量差和/或睡眠时间不足/过长。CVD 事件是指新发冠心病和中风的综合事件。使用 Cox 比例风险模型在 15 年的随访中检查睡眠质量不佳与 CVD 事件之间的关系，并对 CVD 风险预测因素和阻塞性睡眠呼吸暂停进行调整。
样本平均年龄为 54 岁（标准差=13），64%为女性，66%报告睡眠质量不佳。调整 CVD 风险预测因素和阻塞性睡眠呼吸暂停后，睡眠质量不佳与 CVD 事件无关[风险比（95%CI）=1.18（0.97-1.46）]。与推荐的睡眠时间相比，长[风险比（95%CI）=1.32（1.02-1.70）]和非常短[风险比（95%CI）=1.56（1.06-2.30）]的睡眠时间与 CVD 事件相关。低质量睡眠与 CVD 事件无关（p=0.413）。
长和非常短的自我报告睡眠时间但不是自我报告的睡眠质量与 CVD 发病的风险增加有关。
