Lawal Yakubu, Bello Fatima, Kaoje Yazid Suleiman
Federal Medical Centre, Azare, Bauchi, Nigeria.
Ahmadu Bello University Teaching Hospital Zaria, Kaduna, Nigeria.
Clin Diabetes. 2020 Oct;38(4):328-338. doi: 10.2337/cd19-0101.
Evidence increasingly demonstrates that prediabetes is a toxic state, as well as a risk factor for diabetes, and is associated with pathophysiological changes in several tissues and organs. Unfortunately, use of available evidence-based treatments for prediabetes is low. This review seeks to explain why prediabetes must be viewed and treated as a serious pathological entity in its own right. It offers an overview of the pathophysiology and complications of prediabetes and describes how this condition can be reversed if all treatment avenues are deployed early in its course.
越来越多的证据表明，糖尿病前期不仅是糖尿病的一个危险因素，还是一种毒性状态，并且与多个组织和器官的病理生理变化相关。遗憾的是，针对糖尿病前期采用现有循证治疗方法的比例较低。本综述旨在解释为何必须将糖尿病前期视为一种严重的病理实体并进行治疗。它概述了糖尿病前期的病理生理学和并发症，并描述了如果在病程早期采用所有治疗途径，这种情况如何能够逆转。
