Department of Microbiology and Virology, University Hospitals of Leicester NHS Trust, Leicester, UK.
Department of Ophthalmology, University Hospitals of Leicester NHS Trust, Leicester, UK.
J Med Virol. 2021 Jun;93(6):3969-3973. doi: 10.1002/jmv.26647. Epub 2020 Dec 17.
We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D.
我们报告了一起大型流行疾病(n=126),主要是在 2019 年 3 月至 8 月间眼科急诊中观察到的两种腺病毒(AdV)D8 型的角结膜炎。通过病毒测序鉴定的其他 AdV 种类包括 B、C 和 E。尽管存在各种更严重的眼部疾病特征,但不同 AdV 种类之间没有显著差异,在 AdV 种类 B 和 AdV 种类 D 的患者中,同样观察到了类似的假膜形成和角膜炎发生率。