Zakrzewska Aleksandra, Wiącek Marta P, Machalińska Anna
First Department of Ophthalmology, Pomeranian Medical University, Szczecin 70-111, Poland.
Int J Ophthalmol. 2019 Dec 18;12(12):1853-1858. doi: 10.18240/ijo.2019.12.06. eCollection 2019.
To evaluate the impact of central corneal thickness (CCT) and corneal curvature on intraocular pressure (IOP) measurements performed by three different tonometers.
IOP in 132 healthy eyes of 66 participants was measured using three different tonometry techniques: Goldmann applanation tonometer (GAT), Pascal dynamic contour tonometer (DCT), and ICare rebound tonometer (RT). CCT and corneal curvature were assessed.
In healthy eyes, DCT presents significantly higher values of IOP than GAT (17.34±3.69 and 15.27±4.06 mm Hg, <0.0001). RT measurements are significantly lower than GAT (13.56±4.33 mm Hg, <0.0001). Compared with GAT, DCT presented on average 2.51 mm Hg higher values in eyes with CCT<600 µm and 0.99 mm Hg higher results in eyes with CCT≥600 µm. The RT results were lower on average by 1.61 and 1.95 mm Hg than those obtained by GAT, respectively. Positive correlations between CCT in eyes with CCT<600 µm were detected for all IOP measurement techniques, whereas a similar relationship was not observed in eyes with thicker corneas. A correlation between IOP values and keratometry in the group with CCT<600 µm was not detected with any of the tonometry methods. In thicker corneas, a positive correlation was found for GAT and mean keratometry values (=0.369, =0.005).
The same method should always be chosen for routine IOP control, and measurements obtained by different methods cannot be compared. All analysed tonometry methods are dependent on CCT; thus, CCT should be taken into consideration for both diagnostics and monitoring.
评估中央角膜厚度（CCT）和角膜曲率对三种不同眼压计测量眼压（IOP）的影响。
使用三种不同的眼压测量技术对66名参与者的132只健康眼睛进行眼压测量：Goldmann压平眼压计（GAT）、Pascal动态轮廓眼压计（DCT）和ICare回弹眼压计（RT）。评估CCT和角膜曲率。
在健康眼睛中，DCT测量的眼压值显著高于GAT（分别为17.34±3.69和15.27±4.06 mmHg，<0.0001）。RT测量值显著低于GAT（13.56±4.33 mmHg，<0.0001）。与GAT相比，在CCT<600 µm的眼睛中，DCT测量值平均高2.51 mmHg，在CCT≥600 µm的眼睛中高0.99 mmHg。RT测量结果分别比GAT平均低1.61和1.95 mmHg。对于所有眼压测量技术，在CCT<600 µm的眼睛中检测到CCT与眼压之间存在正相关，而在角膜较厚的眼睛中未观察到类似关系。使用任何一种眼压测量方法均未在CCT<600 µm的组中检测到眼压值与角膜曲率之间的相关性。在较厚的角膜中，发现GAT与平均角膜曲率值之间存在正相关（=0.369，=0.005）。
常规眼压控制应始终选择相同的方法，不同方法获得的测量结果无法进行比较。所有分析的眼压测量方法均依赖于CCT；因此，在诊断和监测中均应考虑CCT。
