Omidfar Kobra, Ahmadi Anita, Syedmoradi Leila, Khoshfetrat Seyyed Mehdi, Larijani Bagher
Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, 14395/1179, Tehran, I.R. Iran.
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2020 Oct 28;23(2):1-5. doi: 10.1007/s40200-020-00668-0.
The growing demand of diagnostic tools with enhanced analytical characteristics in term of sensitivity, selectivity, and low response time has encouraged researches to conduct their research towards development of point-of-care (POC) biosensors. POC diagnostic devices are powerful tools for detection, diagnosis, and monitoring of diseases at its initial stage. The above characteristics encouraged us to conduct active multidisciplinary and collaborative research oriented towards the design and development of POC sensing systems. Here, we present a brief overview of our recent achievement in the field of biomedical POC devices implemented in paper based microfluidic and screen printing electrodes and discuss the critical limitations that need to be surmounted to facilitate their translation into clinical practice in the future.
对具有更高分析特性（在灵敏度、选择性和低响应时间方面）的诊断工具的需求不断增长，促使研究人员开展研究以开发即时检测（POC）生物传感器。POC诊断设备是在疾病初期进行检测、诊断和监测的有力工具。上述特性促使我们开展积极的多学科合作研究，致力于POC传感系统的设计与开发。在此，我们简要概述了我们在基于纸基微流体和丝网印刷电极的生物医学POC设备领域的最新成果，并讨论了未来为促进其转化为临床实践需要克服的关键限制。
