Coffaro K A, Hinegardner R T
Science. 1977 Sep 30;197(4311):1389-90. doi: 10.1126/science.331476.
The sea urchin shows an immune response to grafted tissue similar to that found in vertebrates. Unrelated animals rejected allografts in about 30 days. Acceptance of allografts was observed for tissue exchanged between some F2 and F3 inbred animals. The percentage of acceptances reflected the degree of inbreeding. Accelerated second set rejection was also found. These grafts were rejected in one-third of the time compared to first sets.
海胆对移植组织的免疫反应与在脊椎动物中发现的相似。不相关的动物在约30天内排斥同种异体移植物。在一些F2和F3近交动物之间交换的组织中观察到同种异体移植物被接受。接受的百分比反映了近亲繁殖的程度。还发现了加速的二次排斥反应。与首次移植相比，这些移植物在三分之一的时间内被排斥。
