Nowogrodski Chen, Simon Ido, Magdassi Shlomo, Shoseyov Oded
Plant Molecular Biology and Nano Biotechnology, Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.
Casali Center of Applied Chemistry, Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91905, Israel.
Polymers (Basel). 2020 Nov 2;12(11):2568. doi: 10.3390/polym12112568.
Second skin is a topically applied, skin-conforming material that mimics human skin properties and bears potential cosmetic and e-skin applications. To successfully integrate with natural skin, characteristics such as color and skin features must be matched. In this work, we prepared bio-based skin-like films from cross-linked keratin/melanin films (KMFs), using a simple fabrication method and non-toxic materials. The films retained their stability in aqueous solutions, showed skin-like mechanical properties, and were homogenous and handleable, with non-granular surfaces and a notable cross-linked structure as determined by attenuated total reflection (ATR). In addition, the combination of keratin and melanin allowed for adjustable tones similar to those of natural human skin. Furthermore, KMFs showed light transmittance and UV-blocking (up to 99%) as a function of melanin content. Finally, keratin/melanin ink (KMI) was used to inkjet-print high-resolution images with natural skin pigmented features. The KMFs and KMI may offer advanced solutions as e-skin or cosmetics platforms.
第二层皮肤是一种局部应用的、贴合皮肤的材料，它模仿人类皮肤特性，具有潜在的化妆品和电子皮肤应用。为了成功地与天然皮肤融合，颜色和皮肤特征等特性必须匹配。在这项工作中，我们使用简单的制造方法和无毒材料，从交联角蛋白/黑色素膜（KMF）制备了生物基类皮肤薄膜。这些薄膜在水溶液中保持稳定性，表现出类皮肤的机械性能，均匀且易于处理，表面无颗粒，通过衰减全反射（ATR）测定具有显著的交联结构。此外，角蛋白和黑色素的组合产生了与天然人类皮肤相似的可调节色调。此外，KMF的透光率和紫外线阻挡率（高达99%）随黑色素含量而变化。最后，角蛋白/黑色素墨水（KMI）被用于喷墨打印具有天然皮肤色素特征的高分辨率图像。KMF和KMI可能作为电子皮肤或化妆品平台提供先进的解决方案。
