Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Sector for Evidence-based Healthcare,National Institutes of Health, Ministry of Health, Shah Alam, Selangor, Malaysia.
BMJ Open. 2020 Nov 4;10(11):e039623. doi: 10.1136/bmjopen-2020-039623.
The current global pandemic of the virus that emerged from Hubei province in China has caused coronavirus disease in 2019 (COVID-19), which has affected a total number of 900 036 people globally, involving 206 countries and resulted in a cumulative of 45 693 deaths worldwide as of 3 April 2020. The mode of transmission is identified through airdrops from patients' body fluids such as during sneezing, coughing and talking. However, the relative importance of environmental effects in the transmission of the virus has not been vastly studied. In addition, the role of temperature and humidity in air-borne transmission of infection is presently still unclear. This study aims to identify the effect of temperature, humidity and air quality in the transmission of SARS-CoV-2.
We will systematically conduct a comprehensive literature search using various databases including PubMed, EMBASE, Scopus, CENTRAL and Google Scholar to identify potential studies. The search will be performed for any eligible articles from the earliest published articles up to latest available studies in 2020. We will include all the observational studies such as cohort case-control and cross-sectional studies that explains or measures the effects of temperature and/or humidity and/or air quality and/or anthropic activities that is associated with SARS-CoV-2. Study selection and reporting will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and Meta-Analysis of Observational Studies in Epidemiology guideline. All data will be extracted using a standardised data extraction form and quality of the studies will be assessed using the Newcastle-Ottawa Scale guideline. Descriptive and meta-analysis will be performed using a random effect model in Review Manager File.
No primary data will be collected, and thus no formal ethical approval is required. The results will be disseminated through a peer-reviewed publication and conference presentation.
CRD42020176756.
当前源自中国湖北省的病毒引发的全球大流行导致了 2019 年冠状病毒病（COVID-19），截至 2020 年 4 月 3 日，该病已在全球范围内影响了 900036 人，涉及 206 个国家和地区，造成全球累计 45693 人死亡。传播途径已确定为通过患者体液（如打喷嚏、咳嗽和说话时）飞沫传播。然而，环境因素在病毒传播中的相对重要性尚未得到广泛研究。此外，温度和湿度在空气传播感染中的作用目前仍不清楚。本研究旨在确定温度、湿度和空气质量对 SARS-CoV-2 传播的影响。
我们将系统地使用各种数据库（包括 PubMed、EMBASE、Scopus、CENTRAL 和 Google Scholar）进行全面的文献检索，以确定潜在的研究。检索将从最早发表的文章到 2020 年最新的可用研究，对所有合格的文章进行。我们将包括所有观察性研究，如队列病例对照和横断面研究，这些研究解释或衡量了温度和/或湿度和/或空气质量和/或与 SARS-CoV-2 相关的人为活动的影响。研究选择和报告将遵循系统评价和荟萃分析（PRISMA）指南和观察性研究荟萃分析的流行病学指南。所有数据将使用标准化数据提取表进行提取，并使用纽卡斯尔-渥太华量表指南评估研究质量。描述性和荟萃分析将在 Review Manager File 中使用随机效应模型进行。
不会收集原始数据，因此不需要正式的伦理批准。结果将通过同行评审的出版物和会议报告进行传播。
PROSPERO 注册号：CRD42020176756。
