Shih Ya-Wen, Hung Chin-Sheng, Huang Cheng-Chiao, Chou Kuei-Ru, Niu Shu-Fen, Chan Sally, Tsai Hsiu-Ting
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Cancer Manag Res. 2020 Oct 29;12:10799-10807. doi: 10.2147/CMAR.S267415. eCollection 2020.
Breast cancer is a common malignancy worldwide. Smartphones have gradually become indispensable to our modern lives and have already changed lifestyles of human beings. To our best knowledge, no study has investigated the relationship between smartphone use and breast cancer. This case-control study purposely investigated the relationship between smartphone use and breast cancer risk.
This was a case-control study comprising 894 healthy controls and 211 patients with breast cancer. All participants were asked to respond to standard questionnaires to collect information on sleep quality, smartphone addiction, and smartphone use.
Participants with smartphone addiction had a significantly higher 1.43-fold risk of breast cancer. Individuals with the habitual behavior of smartphone use >4.5 minutes before bedtime had a significantly increased 5.27-fold risk of breast cancer compared to those who used a smartphone for ≤4.5 minutes before bedtime. Additionally, a closer distance between the smartphone and the breasts when using the smartphone exhibited a significantly increased 1.59-fold risk. Participants who carried their smartphone near their chest or waist-abdomen area had significantly increased 5.03-fold and 4.06-fold risks of breast cancer, respectively, compared to those who carried the smartphone below the waist. Moreover, there was a synergistic effect of smartphone addiction and smartphone use of >4.5 minutes before bedtime which increased the breast cancer risk.
Excessive smartphone use significantly increased the risk of breast cancer, particularly for participants with smartphone addiction, a close distance between the breasts and smartphone, and the habit of smartphone use before bedtime.
乳腺癌是全球常见的恶性肿瘤。智能手机已逐渐成为我们现代生活中不可或缺的一部分，并已经改变了人类的生活方式。据我们所知，尚无研究调查智能手机使用与乳腺癌之间的关系。本病例对照研究旨在调查智能手机使用与乳腺癌风险之间的关系。
这是一项病例对照研究，包括894名健康对照者和211名乳腺癌患者。所有参与者均被要求回答标准问卷，以收集有关睡眠质量、智能手机成瘾和智能手机使用情况的信息。
有智能手机成瘾的参与者患乳腺癌的风险显著高出1.43倍。与睡前使用智能手机时间≤4.5分钟的人相比，有睡前使用智能手机超过4.5分钟习惯行为的个体患乳腺癌的风险显著增加5.27倍。此外，使用智能手机时智能手机与乳房之间距离更近，患癌风险显著增加1.59倍。与将智能手机放在腰部以下的人相比，将智能手机放在胸部或腰腹部附近的参与者患乳腺癌的风险分别显著增加5.03倍和4.06倍。此外，智能手机成瘾与睡前使用智能手机超过4.5分钟之间存在协同效应，会增加患乳腺癌的风险。
过度使用智能手机会显著增加患乳腺癌的风险，特别是对于有智能手机成瘾、乳房与智能手机距离近以及有睡前使用智能手机习惯的参与者。
