Urquhart Elizabeth L, Wanniarachchi Hashini, Wang Xinlong, Gonzalez-Lima Francisco, Alexandrakis George, Liu Hanli
University of Texas at Arlington, Department of Bioengineering, Arlington, TX 76010, USA.
University of Texas at Austin, Department of Psychology and Institute for Neuroscience, Austin, TX 78712, USA.
Biomed Opt Express. 2020 Sep 22;11(10):5783-5799. doi: 10.1364/BOE.402047. eCollection 2020 Oct 1.
Transcranial photobiomodulation (tPBM) with near-infrared light on the human head has been shown to enhance human cognition. In this study, tPBM-induced effects on resting state brain networks were investigated using 111-channel functional near-infrared spectroscopy over the whole head. Measurements were collected with and without 8-minute tPBM in 19 adults. Functional connectivity (FC) and brain network metrics were quantified using Pearson's correlation coefficients and graph theory analysis (GTA), respectively, for the periods of pre-, during, and post-tPBM. Our results revealed that tPBM (1) enhanced information processing speed and efficiency of the brain network, and (2) increased FC significantly in the frontal-parietal network, shedding light on a better understanding of tPBM effects on brain networks.
经颅光生物调节（tPBM）使用近红外光照射人类头部已被证明可增强人类认知能力。在本研究中，使用全头部111通道功能近红外光谱研究了tPBM对静息态脑网络的影响。在19名成年人中分别在进行8分钟tPBM前后收集测量数据。分别使用皮尔逊相关系数和图论分析（GTA）对tPBM前、期间和后的功能连接性（FC）和脑网络指标进行量化。我们的结果表明，tPBM（1）提高了脑网络的信息处理速度和效率，（2）显著增加了额顶网络中的FC，这有助于更好地理解tPBM对脑网络的影响。
