Suppr超能文献

老年与非老年重伤患者的预后有差异吗?——一项为期七年的回顾性观察队列研究及配对分析

Is There Any Difference in the Outcome of Geriatric and Non-Geriatric Severely Injured Patients?-A Seven-Year, Retrospective, Observational Cohort Study with Matched-Pair Analysis.

作者信息

Jensen Kai O, Lempert Maximilian, Sprengel Kai, Simmen Hans P, Pothmann Carina, Schlögl Mathias, Bischoff-Ferrari Heike A, Hierholzer Christian, Pape Hans C, Neuhaus Valentin

机构信息

Department of Trauma, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.

University Clinic for Acute Geriatric Care, City Hospital Waid, 8037 Zurich, Switzerland.

出版信息

J Clin Med. 2020 Nov 3;9(11):3544. doi: 10.3390/jcm9113544.

Abstract

Geriatric trauma is expected to increase due to the lifestyle and activity of the aging population and will be among the major future challenges in health care. Therefore, the aim of this study was to investigate differences between polytraumatized geriatric and non-geriatric patients regarding mortality, length-of-stay and complications with a matched pair analysis. We included patients older than 17 years with an Injury Severity Score (ISS) of 16 or more admitted to our level 1 trauma center between January 2008 and December 2015. The cohort was stratified into two groups (age < 70 and ≥ 70 years). One-to-one matching was performed based on gender, ISS, mechanism of injury (penetrating/blunt), Glasgow coma scale (GCS), base excess, and the presence of coagulopathy (international normalized ratio (INR) ≥ 1.4). Outcome was compared using the paired -test and McNemar-test. A total of 1457 patients were identified. There were 1022 male (70%) and 435 female patients. Three hundred and sixty-four patients (24%) were older than 70 years. Matching resulted in 57 pairs. Mortality as well as length-of-stay were comparable between geriatric and non-geriatric polytraumatized patients. Complication rate (34% vs. 56%, = 0.031) was significantly higher in geriatric patients. This indicates the possibility of similar outcomes in geriatric polytraumatized patients receiving optimal care.

摘要

由于老年人口的生活方式和活动情况,预计老年创伤病例将会增加,这将成为未来医疗保健领域的主要挑战之一。因此,本研究的目的是通过配对分析,调查多发伤老年患者和非老年患者在死亡率、住院时间和并发症方面的差异。我们纳入了2008年1月至2015年12月期间入住我们一级创伤中心、年龄在17岁以上且损伤严重程度评分(ISS)为16分或更高的患者。该队列被分为两组(年龄<70岁和≥70岁)。根据性别、ISS、损伤机制(穿透伤/钝性伤)、格拉斯哥昏迷量表(GCS)、碱剩余以及是否存在凝血病(国际标准化比值(INR)≥1.4)进行一对一匹配。使用配对t检验和McNemar检验比较结果。共确定了1457例患者。其中男性1022例(70%),女性435例。364例患者(24%)年龄超过70岁。匹配后得到57对。老年和非老年多发伤患者的死亡率和住院时间相当。老年患者的并发症发生率(34%对56%,P = 0.031)显著更高。这表明接受最佳治疗的老年多发伤患者有可能获得相似的治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8e/7692238/cf414e8c7050/jcm-09-03544-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验