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外周性牙源性角化囊肿:两例新病例报告及文献复习

Peripheral odontogenic keratocyst: Report of two new cases and review of the literature.

作者信息

Rodrigues Bruno-Teixeira-Gonçalves, Israel Mônica-Simões, de Moura Kenia-Lorena-Monteiro, Pinheiro Giulianna-Lima, Carlos Roman, Pires Fábio-Ramoa

机构信息

DDS, Dental School, State University of Rio de Janeiro, Rio de Janeiro, Brazil.

DDS, PhD, Stomatology, Department of Diagnosis and Therapeutics, Dental School, State University of Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

J Clin Exp Dent. 2020 Oct 1;12(10):e1005-e1010. doi: 10.4317/jced.57653. eCollection 2020 Oct.

DOI:10.4317/jced.57653
PMID:33154804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7600203/
Abstract

Peripheral odontogenic keratocyst (POKC) is a rare soft tissue entity showing the same histological characteristics of odontogenic keratocyst. Herein, we report two cases of POKC affecting the gingiva/alveolar mucosa. Case 1. A 43-year-old female was referred for evaluation of a painless well-defined nodular, sessile, non-tender swelling in the right maxillary buccal gingiva. No radiological alterations were observed. The patient was submitted to excisional biopsy and histological diagnosis was POKC. There were no signs of local recurrence after a 4-year follow-up. Case 2. A 63-year-old female was referred for evaluation of a painless well-defined nodular, sessile, yellowish swelling in the anterior mandibular alveolar mucosa. No radiological alterations were observed. The patient was submitted to excisional biopsy and histological diagnosis was POKC. Patient recovery was uneventful but she did not return for follow-up. POKC should be considered in the differential diagnosis of gingival cystic swellings and can be managed through conservative surgery. Odontogenic keratocyst, peripheral, gingiva, alveolar mucosa.

摘要

外周性牙源性角化囊肿(POKC)是一种罕见的软组织病变,具有与牙源性角化囊肿相同的组织学特征。在此,我们报告两例累及牙龈/牙槽黏膜的POKC病例。病例1。一名43岁女性因右侧上颌颊侧牙龈出现无痛性边界清晰的结节状、无柄、无压痛肿胀而前来评估。未观察到放射学改变。患者接受了切除活检,组织学诊断为POKC。4年随访后无局部复发迹象。病例2。一名63岁女性因下颌前牙槽黏膜出现无痛性边界清晰的结节状、无柄、淡黄色肿胀而前来评估。未观察到放射学改变。患者接受了切除活检,组织学诊断为POKC。患者恢复顺利,但未返回进行随访。在牙龈囊性肿胀的鉴别诊断中应考虑POKC,可通过保守手术进行处理。牙源性角化囊肿,外周性,牙龈,牙槽黏膜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/060fb6c7889d/jced-12-e1005-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/17e84bc8c605/jced-12-e1005-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/818a286a0aeb/jced-12-e1005-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/060fb6c7889d/jced-12-e1005-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/17e84bc8c605/jced-12-e1005-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/818a286a0aeb/jced-12-e1005-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308e/7600203/060fb6c7889d/jced-12-e1005-g003.jpg

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本文引用的文献

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SAGE Open Med Case Rep. 2019 May 19;7:2050313X19849828. doi: 10.1177/2050313X19849828. eCollection 2019.
2
Maxillary peripheral keratocystic odontogenic tumor. A clinical case report.上颌骨外周性角化囊性牙源性肿瘤。一例临床病例报告。
J Clin Exp Dent. 2017 Jan 1;9(1):e167-e171. doi: 10.4317/jced.53438. eCollection 2017 Jan.
3
A Large Extragnathic Keratocystic Odontogenic Tumour.
一例巨大颌骨外牙源性角化囊性瘤
Case Rep Pathol. 2015;2015:723010. doi: 10.1155/2015/723010. Epub 2015 Dec 6.
4
Clinical, radiological and therapeutic features of keratocystic odontogenic tumours: a study over a decade.牙源性角化囊性瘤的临床、影像学及治疗特征:一项长达十年的研究
J Clin Exp Dent. 2014 Jul 1;6(3):e259-64. doi: 10.4317/jced.51408. eCollection 2014 Jul.
5
Radiological and clinical features of peripheral keratocystic odontogenic tumor.外周型牙源性角化囊性瘤的放射学及临床特征
Int J Clin Exp Med. 2014 Jan 15;7(1):300-6. eCollection 2014.
6
Peripheral odontogenic keratocyst associated with nevoid basal cell carcinoma syndrome: a case report.外周性牙源性角化囊肿伴痣样基底细胞癌综合征:一例报告
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