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利用空间约束和三维特征对脑部磁共振成像扫描进行分割。

Segmentation of MRI brain scans using spatial constraints and 3D features.

作者信息

Grande-Barreto Jonas, Gómez-Gil Pilar

机构信息

National Institute for Astrophysics, Optics and Electronics (INAOE), Puebla, Mexico.

出版信息

Med Biol Eng Comput. 2020 Dec;58(12):3101-3112. doi: 10.1007/s11517-020-02270-1. Epub 2020 Nov 5.

DOI:10.1007/s11517-020-02270-1
PMID:33155095
Abstract

This paper presents a novel unsupervised algorithm for brain tissue segmentation in magnetic resonance imaging (MRI). The proposed algorithm, named Gardens2, adopts a clustering approach to segment voxels of a given MRI into three classes: cerebrospinal fluid (CSF), gray matter (GM), and white matter (WM). Using an overlapping criterion, 3D feature descriptors and prior atlas information, Gardens2 generates a segmentation mask per class in order to parcellate the brain tissues. We assessed our method using three neuroimaging datasets: BrainWeb, IBSR18, and IBSR20, the last two provided by the Internet Brain Segmentation Repository. Its performance was compared with eleven well established as well as newly proposed unsupervised segmentation methods. Overall, Gardens2 obtained better segmentation performance than the rest of the methods in two of the three databases and competitive results when its performance was measured by class. Graphical Abstract Brain tissue segmentation using 3D features and an adjusted atlas template.

摘要

本文提出了一种用于磁共振成像(MRI)中脑组织分割的新型无监督算法。所提出的算法名为Gardens2,采用聚类方法将给定MRI的体素分割为三类:脑脊液(CSF)、灰质(GM)和白质(WM)。利用重叠准则、3D特征描述符和先验图谱信息,Gardens2为每个类别生成一个分割掩码,以便对脑组织进行分区。我们使用三个神经影像数据集评估了我们的方法:BrainWeb、IBSR18和IBSR20,后两个数据集由互联网脑图谱库提供。将其性能与十一种成熟的以及新提出的无监督分割方法进行了比较。总体而言,Gardens2在三个数据库中的两个中获得了比其他方法更好的分割性能,并且按类别衡量其性能时得到了具有竞争力的结果。图形摘要 使用3D特征和调整后的图谱模板进行脑组织分割。

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本文引用的文献

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BMC Med Imaging. 2018 May 9;18(1):9. doi: 10.1186/s12880-018-0252-x.
2
Delineation of the ischemic stroke lesion based on watershed and relative fuzzy connectedness in brain MRI.基于分水岭和相对模糊连通性的脑 MRI 缺血性脑卒中病灶描绘。
Med Biol Eng Comput. 2018 May;56(5):795-807. doi: 10.1007/s11517-017-1726-7. Epub 2017 Sep 26.
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Accurate Lungs Segmentation on CT Chest Images by Adaptive Appearance-Guided Shape Modeling.基于自适应外观引导形状建模的 CT 胸部图像肺部精确分割。
IEEE Trans Med Imaging. 2017 Jan;36(1):263-276. doi: 10.1109/TMI.2016.2606370. Epub 2016 Sep 12.
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Deformable Registration of Biomedical Images Using 2D Hidden Markov Models.使用二维隐马尔可夫模型的生物医学图像变形配准
IEEE Trans Image Process. 2016 Oct;25(10):4631-4640. doi: 10.1109/TIP.2016.2592702. Epub 2016 Jul 18.
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Automatic brain tissue segmentation in MR images using Random Forests and Conditional Random Fields.使用随机森林和条件随机场对磁共振图像中的脑组织进行自动分割。
J Neurosci Methods. 2016 Sep 1;270:111-123. doi: 10.1016/j.jneumeth.2016.06.017. Epub 2016 Jun 18.
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3D cerebral MR image segmentation using multiple-classifier system.使用多分类器系统的3D脑磁共振图像分割
Med Biol Eng Comput. 2017 Mar;55(3):353-364. doi: 10.1007/s11517-016-1483-z. Epub 2016 May 20.
7
Resource atlases for multi-atlas brain segmentations with multiple ontology levels based on T1-weighted MRI.基于T1加权磁共振成像的具有多个本体层次的多图谱脑部分割资源图谱集。
Neuroimage. 2016 Jan 15;125:120-130. doi: 10.1016/j.neuroimage.2015.10.042. Epub 2015 Oct 21.
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Hierarchical max-flow segmentation framework for multi-atlas segmentation with Kohonen self-organizing map based Gaussian mixture modeling.基于 Kohonen 自组织映射的高斯混合模型的多图谱分割的分层最大流分割框架。
Med Image Anal. 2016 Jan;27:45-56. doi: 10.1016/j.media.2015.05.005. Epub 2015 May 29.
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Neurobiol Aging. 2015 Jan;36 Suppl 1(0 1):S121-31. doi: 10.1016/j.neurobiolaging.2014.04.037. Epub 2014 Aug 30.
10
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