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癫痫-定义、分类、病理生理学和流行病学。

Epilepsy-Definition, Classification, Pathophysiology, and Epidemiology.

机构信息

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, California.

出版信息

Semin Neurol. 2020 Dec;40(6):617-623. doi: 10.1055/s-0040-1718719. Epub 2020 Nov 5.

DOI:10.1055/s-0040-1718719
PMID:33155183
Abstract

Seizures affect the lives of 10% of the global population and result in epilepsy in 1 to 2% of people around the world. Current knowledge about etiology, diagnosis, and treatments for epilepsy is constantly evolving. As more is learned, appropriate and updated definitions and classification systems for seizures and epilepsy are of the utmost importance. Without proper definitions and classification, many individuals will be improperly diagnosed and incorrectly treated. It is also essential for research purposes to have proper definitions, so that appropriate populations can be identified and studied. Imprecise definitions, failure to use accepted terminology, or inappropriate use of terminology hamper our ability to study and advance the field of epilepsy. This article begins by discussing the pathophysiology and epidemiology of epilepsy, and then covers the accepted contemporary definitions and classifications of seizures and epilepsies.

摘要

癫痫影响全球 10%的人口的生活,导致全球 1%至 2%的人患有癫痫。目前,关于癫痫的病因、诊断和治疗的知识不断发展。随着更多知识的积累,对于癫痫发作和癫痫的适当和更新的定义和分类系统至关重要。如果没有适当的定义和分类,许多人将被误诊和错误治疗。对于研究目的而言,适当的定义也是必不可少的,以便能够识别和研究合适的人群。不精确的定义、未能使用公认的术语或不适当使用术语会妨碍我们研究和推进癫痫领域的能力。本文首先讨论了癫痫的病理生理学和流行病学,然后介绍了目前公认的癫痫发作和癫痫的定义和分类。

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