Vettorazzi G
Department of Toxicology, University of Milan, Italy.
Food Addit Contam. 1987 Oct-Dec;4(4):331-56. doi: 10.1080/02652038709373645.
The Acceptable Daily Intake (ADI) is an internationally recognized quantified expression of the acceptability of food additives. It embraces both a concept and a numerical expression. This paper describes the conceptual origin and progression of this instrument of risk assessment and management in the framework of its history which encompasses three sequential stages: developmental, consolidation and contemporary periods. The review narrates in retrospect how the ADI originated, how it developed, and delineates in prospective its future evolution in the light of advances in the safety evaluation of food additives.
每日允许摄入量（ADI）是食品添加剂可接受性的国际公认量化表述。它包含一个概念和一个数值表达。本文在其历史框架内描述了这一风险评估与管理工具的概念起源和发展过程，该历史涵盖三个连续阶段：发展期、巩固期和当代时期。这篇综述回顾了ADI是如何起源、如何发展的，并根据食品添加剂安全评估的进展前瞻性地描绘了其未来的演变。
