TMDC 在医学诊断中的最新进展。
Recent advances on TMDCs for medical diagnosis.
机构信息
College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China; Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen, 518000, China.
College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518000, China.
出版信息
Biomaterials. 2021 Feb;269:120471. doi: 10.1016/j.biomaterials.2020.120471. Epub 2020 Oct 27.
Transition metal dichalcogenides (TMDCs), such as MoS and WS, have attracted much attention in biosensing and bioimaging due to its excellent stability, biocompatibility, high specific surface area, and wide varieties. In this review, we overviewed the application of TMDCs in biosensing and bioimaging. Firstly, the synthesis methods and surface functionalization methods of TMDCs were summarized. Secondly, according to the working mechanism, we classified and gave a detailed account of the latest research progress of TMDC-based biosensing for the detection of the enzyme, DNA, and other biological molecules. Then, we outlined the recent progress of applying TMDCs in bio-imaging, including fluorescence, X-ray computed tomographic, magnetic response imaging, photographic and multimodal imaging, respectively. Finally, we discussed the future challenges and development direction of the application of TMDCs in medical diagnosis. Also, we put forward our view on the opportunity of TMDCs in the big data of modern medical diagnosis.
过渡金属二卤化物（TMDCs），如 MoS 和 WS，由于其优异的稳定性、生物相容性、高比表面积和种类繁多，在生物传感和生物成像领域引起了广泛关注。在这篇综述中，我们概述了 TMDCs 在生物传感和生物成像中的应用。首先，总结了 TMDCs 的合成方法和表面功能化方法。其次，根据工作机制，我们对基于 TMDC 的生物传感用于检测酶、DNA 和其他生物分子的最新研究进展进行了分类和详细阐述。然后，概述了 TMDCs 在荧光、X 射线计算机断层扫描、磁响应成像、摄影和多模态成像等生物成像中的最新应用进展。最后，讨论了 TMDCs 在医学诊断中应用的未来挑战和发展方向。此外，我们还对 TMDCs 在现代医学诊断大数据中的机遇提出了看法。
Zotero 插件