Balasch J, Vanrell J A
Department of Obstetrics and Gynaecology, Facultad de Medicina, Hospital Clínico y Provincial, Barcelona, Spain.
Hum Reprod. 1987 Oct;2(7):557-67. doi: 10.1093/oxfordjournals.humrep.a136589.
This paper analyses different controversial aspects of luteal phase deficiency (LPD) on the basis of our own data and current clinical experience. Conceptual and diagnostic concerns include: (i) the lack of predictive value of mid-luteal plasma progesterone determinations regarding the progestational transformation of the endometrium, and (ii) the need for a minimum of two, or even three, endometrial biopsies for diagnosis of LPD. From an aetiologic point of view follicular phase determinants of LPD are emphasized and conflicting data on claimed predisposing factors of LPD are analysed. Primary therapeutic approaches to LPD and the effectiveness and significance of such therapy on fertility are discussed.
本文基于我们自己的数据和当前临床经验，分析了黄体期缺陷（LPD）的不同争议方面。概念和诊断方面的问题包括：（i）黄体中期血浆孕酮测定对子宫内膜孕激素转化缺乏预测价值；（ii）诊断LPD至少需要进行两次甚至三次子宫内膜活检。从病因学角度强调了LPD的卵泡期决定因素，并分析了关于LPD所谓易感因素的相互矛盾的数据。讨论了LPD的主要治疗方法以及这种治疗对生育能力的有效性和意义。
