Balasch J
Department of Obstetrics and Gynecology, Faculty of Medicine, Hospital Clínico y Provincial, Barcelona, Spain.
J Steroid Biochem. 1987;27(1-3):393-7. doi: 10.1016/0022-4731(87)90332-3.
The author analyzes different controversial clinical aspects of luteal phase insufficiency (LPI) on the basis of his own data. Conceptual and diagnostic concerns include: (1) the lack of predictive value of midluteal plasma progesterone determination regarding the progestational transformation of the endometrium, and (2) the need for a minimum of two, and even three, endometrial biopsies for diagnosis of LPI. From an etiologic point of view, follicular phase determinants of LPI are emphasized. Primary therapeutic approaches of LPI and the effectiveness and significance of such therapy on fertility are discussed.
作者基于自身数据，分析了黄体期缺陷（LPI）不同的有争议的临床方面。概念和诊断方面的问题包括：（1）黄体中期血浆孕酮测定对于子宫内膜孕激素转化缺乏预测价值；（2）诊断LPI至少需要进行两次甚至三次子宫内膜活检。从病因学角度，强调了LPI的卵泡期决定因素。讨论了LPI的主要治疗方法以及这种治疗对生育能力的有效性和意义。
