减少尼古丁香烟在实验烟草市场监管环境下的影响:一项随机试验。

Effects of Reduced-Nicotine Cigarettes Across Regulatory Environments in the Experimental Tobacco Marketplace: A Randomized Trial.

机构信息

Department of Family and Community Medicine, University of Kentucky College of Medicine, Lexington, KY.

Department of Statistics, Virginia Tech, Blacksburg, VA.

出版信息

Nicotine Tob Res. 2021 Jun 8;23(7):1123-1132. doi: 10.1093/ntr/ntaa226.

Abstract

INTRODUCTION

Cigarette smoking remains the leading preventable cause of death in the United States. Recent efforts have explored the potential health and policy benefits of reducing nicotine, an addictive component, in combustible cigarettes. To date, an experimental, prospective analysis directly comparing the effects of varying regulatory environments on purchases of multiple products has yet to be conducted. The present study compared real purchasing of conventional cigarettes, reduced-nicotine cigarettes, and a variety of other nicotine and tobacco products across a range of regulatory environments.

METHODS

Participants were assigned to one of five groups, each associated with a different nicotine level (mg of nicotine to g of tobacco) in SPECTRUM investigational cigarettes (15.8, 5.2, 2.4, 1.3, and 0.4 mg/g). Across sessions, participants made real purchases for nicotine/tobacco products in an Experimental Tobacco Marketplace. Each session corresponded with a distinct regulatory environment wherein different nicotine/tobacco products were available for purchase.

RESULTS

Our results suggest that the primary drivers of cigarette and nicotine purchasing are regulatory environment and the presence/absence of alternative nicotine and tobacco products. Perhaps surprisingly, nicotine level does not appear to be such a driver of purchasing behavior under these experimental conditions. Investigational cigarette purchasing is lowest when other preferred combustible products are available and highest when investigational cigarettes are the only combustible product available for purchase.

CONCLUSIONS

If a reduced-nicotine policy is implemented, great care should be taken in determining and making available less-harmful nicotine/tobacco products as the availability of preferred combustible products may result in undesirable levels of purchasing.

IMPLICATIONS

This is the first experimental study investigating different potential regulatory effects related to a reduced-nicotine policy by examining purchasing across a range of nicotine/tobacco products. Our results suggest the presence of affordable, highly preferred combustible products is likely to maintain tobacco purchasing at undesirable levels. To promote switching to less-harmful products, affordable alternate nicotine and tobacco products should be readily available. Finally, our results suggest that the availability of noncigarette products, not cigarette nicotine level, will most likely affect purchasing of reduced-nicotine cigarettes.

摘要

简介

吸烟仍然是美国可预防的主要死因。最近的研究探索了降低可燃香烟中尼古丁(一种成瘾成分)的潜在健康和政策益处。迄今为止,尚未进行一项直接比较不同监管环境对多种产品购买影响的实验性前瞻性分析。本研究比较了在一系列监管环境下,传统香烟、低尼古丁香烟以及各种其他尼古丁和烟草产品的实际购买情况。

方法

参与者被分配到五个组中的一个,每个组与 SPECTRUM 研究香烟中的不同尼古丁水平(mg 尼古丁/g 烟草)相关联(15.8、5.2、2.4、1.3 和 0.4mg/g)。在各次会议中,参与者在实验性烟草市场中购买实际的尼古丁/烟草产品。每次会议都对应于不同的监管环境,其中可以购买不同的尼古丁/烟草产品。

结果

我们的研究结果表明,香烟和尼古丁购买的主要驱动因素是监管环境以及替代尼古丁和烟草产品的存在/不存在。也许令人惊讶的是,在这些实验条件下,尼古丁水平似乎不是购买行为的驱动因素。当其他首选可燃产品可用时,香烟和尼古丁的购买量最低,而当研究香烟是唯一可购买的可燃产品时,购买量最高。

结论

如果实施低尼古丁政策,应特别注意确定和提供危害较小的尼古丁/烟草产品,因为首选可燃产品的可用性可能导致不可取的购买水平。

意义

这是第一项通过检查一系列尼古丁/烟草产品的购买情况来研究与低尼古丁政策相关的不同潜在监管影响的实验性研究。我们的研究结果表明,价格合理、高度受欢迎的可燃产品的存在可能会使烟草购买保持在不可取的水平。为了促进转向危害较小的产品,应随时提供价格合理的替代尼古丁和烟草产品。最后,我们的研究结果表明,非香烟产品的可用性而不是香烟尼古丁水平,最有可能影响低尼古丁香烟的购买。

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