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肺移植受者的感染并发症。

Infectious Complications in Lung Transplant Recipients.

机构信息

Division of Infectious Diseases and Immunology, Department of Medicine, New York University School of Medicine, 550 1st Avenue, New York, NY, 10016, USA.

Division of Pulmonary, Critical Care Medicine and Sleep Medicine, Department of Medicine, New York University School of Medicine, 550 1st Avenue, New York, NY, 10016, USA.

出版信息

Lung. 2020 Dec;198(6):879-887. doi: 10.1007/s00408-020-00403-9. Epub 2020 Nov 9.

DOI:10.1007/s00408-020-00403-9
PMID:33169174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7652055/
Abstract

Lung transplantation is a lifesaving intervention for patients with advanced lung disease. Due to a combination of immunosuppression, continuous exposure of the lungs to the environment, and complications at the anastomotic sites, lung transplant recipients are at high risk for infectious complications. The aim of this review is to summarize recent developments in the field of infectious diseases as it pertains to lung transplant recipients.

摘要

肺移植是治疗晚期肺部疾病患者的一种救生干预措施。由于免疫抑制、肺部持续暴露于环境以及吻合部位并发症的综合影响,肺移植受者发生感染并发症的风险很高。本综述旨在总结与肺移植受者相关的传染病领域的最新进展。

相似文献

1
Infectious Complications in Lung Transplant Recipients.肺移植受者的感染并发症。
Lung. 2020 Dec;198(6):879-887. doi: 10.1007/s00408-020-00403-9. Epub 2020 Nov 9.
2
[Infection in lung transplantation].[肺移植中的感染]
Enferm Infecc Microbiol Clin. 2007 Dec;25(10):639-49; quiz 650. doi: 10.1157/13112940.
3
Are heart-lung transplant recipients protected from developing bronchiolitis obliterans syndrome?心肺移植受者是否能免受闭塞性细支气管炎综合征的影响?
Ann Thorac Surg. 2006 Jan;81(1):286-91; discussion 291. doi: 10.1016/j.athoracsur.2005.08.010.
4
Pulmonary infections following lung transplantation.肺移植术后肺部感染。
Thorac Surg Clin. 2012 Aug;22(3):403-12. doi: 10.1016/j.thorsurg.2012.04.006. Epub 2012 Jun 13.
5
Effects of prophylactic use of sirolimus on bronchiolitis obliterans syndrome development in lung transplant recipients.西罗莫司预防肺移植受者闭塞性细支气管炎综合征的效果。
Ann Thorac Surg. 2014 Jan;97(1):268-74. doi: 10.1016/j.athoracsur.2013.07.072. Epub 2013 Oct 8.
6
Cytomegalovirus pneumonitis is a risk for bronchiolitis obliterans syndrome in lung transplantation.巨细胞病毒肺炎是肺移植后闭塞性细支气管炎综合征的一个风险因素。
Am J Respir Crit Care Med. 2010 Jun 15;181(12):1391-6. doi: 10.1164/rccm.200911-1786OC. Epub 2010 Feb 18.
7
Long-term outcomes and management of lung transplant recipients.肺移植受者的长期预后和管理。
Best Pract Res Clin Anaesthesiol. 2017 Jun;31(2):285-297. doi: 10.1016/j.bpa.2017.05.006. Epub 2017 May 30.
8
Risk factors for the development of bronchiolitis obliterans syndrome after lung transplantation.肺移植后闭塞性细支气管炎综合征发生的危险因素。
J Thorac Cardiovasc Surg. 1997 Aug;114(2):195-202. doi: 10.1016/S0022-5223(97)70144-2.
9
Management of cytomegalovirus infection in lung transplant recipients: evidence-based recommendations.肺移植受者巨细胞病毒感染的管理:循证推荐意见
Transplantation. 2005 Jul 27;80(2):157-63. doi: 10.1097/01.tp.0000165430.65645.4f.
10
Fungal infection in lung transplantation.肺移植中的真菌感染
Transpl Infect Dis. 2002;4 Suppl 3:24-31. doi: 10.1034/j.1399-3062.4.s3.4.x.

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Multifocal bowel perforation from angioinvasive aspergillosis after bilateral lung transplantation: a case report and review of the literature.双侧肺移植术后血管侵袭性曲霉病导致的多灶性肠穿孔:一例报告并文献复习
AME Case Rep. 2025 Jul 15;9:91. doi: 10.21037/acr-24-221. eCollection 2025.
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Increasing risk of postlung transplant hospitalizations for infection: An analysis of recent trends.肺移植后因感染住院的风险增加:近期趋势分析。
JHLT Open. 2025 Feb 26;8:100231. doi: 10.1016/j.jhlto.2025.100231. eCollection 2025 May.
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Pneumonia in Transplant Recipients: A Comprehensive Review of Diagnosis and Management.移植受者的肺炎:诊断与管理的全面综述
Cureus. 2024 Nov 14;16(11):e73669. doi: 10.7759/cureus.73669. eCollection 2024 Nov.
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Immunopathology of lung transplantation: from infection to rejection and vice versa.肺移植的免疫病理学:从感染到排斥反应,再到相反方向。
Front Immunol. 2024 Sep 2;15:1433469. doi: 10.3389/fimmu.2024.1433469. eCollection 2024.
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Changes in post-transplant serum testosterone levels in men undergoing lung transplantation: a pilot study using the TriNetX Research Network.肺移植男性患者移植后血清睾酮水平的变化:一项使用TriNetX研究网络的试点研究
Int J Impot Res. 2024 Jun 5. doi: 10.1038/s41443-024-00921-7.
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J Thorac Dis. 2024 Feb 29;16(2):1632-1644. doi: 10.21037/jtd-22-1884. Epub 2024 Feb 27.
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Alterations of lung microbiota in lung transplant recipients with pneumocystis jirovecii pneumonia.肺移植受者肺囊虫肺炎的肺微生物组改变。
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Inhibition of Prostaglandin-Degrading Enzyme 15-PGDH Mitigates Acute Murine Lung Allograft Rejection.抑制前列腺素降解酶 15-PGDH 可减轻急性小鼠肺移植排斥反应。
Lung. 2023 Dec;201(6):591-601. doi: 10.1007/s00408-023-00651-5. Epub 2023 Nov 7.

本文引用的文献

1
COVID-19 in lung transplant patients: A case series.COVID-19 于肺移植患者:病例系列。
Am J Transplant. 2020 Nov;20(11):3234-3238. doi: 10.1111/ajt.16212. Epub 2020 Aug 29.
2
Assessing Solid Organ Donors and Monitoring Transplant Recipients for Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Infection - U.S. Public Health Service Guideline, 2020.评估实体器官捐献者和监测人类免疫缺陷病毒、乙型肝炎病毒和丙型肝炎病毒感染的移植受者-美国卫生与公众服务部 2020 年指南。
MMWR Recomm Rep. 2020 Jun 26;69(4):1-16. doi: 10.15585/mmwr.rr6904a1.
3
COVID-19 in solid organ transplant recipients: Initial report from the US epicenter.COVID-19 于实体器官移植受者:来自美国震中地区的初步报告。
Am J Transplant. 2020 Jul;20(7):1800-1808. doi: 10.1111/ajt.15941. Epub 2020 May 10.
4
Lung transplantation as therapeutic option in acute respiratory distress syndrome for coronavirus disease 2019-related pulmonary fibrosis.肺移植作为治疗 2019 冠状病毒病相关肺纤维化急性呼吸窘迫综合征的一种选择。
Chin Med J (Engl). 2020 Jun 20;133(12):1390-1396. doi: 10.1097/CM9.0000000000000839.
5
Burden and Timeline of Infectious Diseases in the First Year After Solid Organ Transplantation in the Swiss Transplant Cohort Study.瑞士器官移植队列研究:实体器官移植后第一年感染性疾病的负担和时间进程。
Clin Infect Dis. 2020 Oct 23;71(7):e159-e169. doi: 10.1093/cid/ciz1113.
6
Toxoplasmosis in non-cardiac solid organ transplant recipients: A case series and review of literature.非心脏实体器官移植受者中的弓形虫病:病例系列及文献综述
Transpl Infect Dis. 2020 Feb;22(1):e13218. doi: 10.1111/tid.13218. Epub 2019 Dec 12.
7
Pseudomonas aeruginosa and acute rejection independently increase the risk of donor-specific antibodies after lung transplantation.铜绿假单胞菌和急性排斥反应独立增加肺移植后供体特异性抗体的风险。
Am J Transplant. 2020 Apr;20(4):1028-1038. doi: 10.1111/ajt.15687. Epub 2019 Dec 24.
8
The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart-lung transplantation Report-2019; Focus theme: Donor and recipient size match.国际心肺移植学会国际胸科器官移植登记处:2019年第36份成人肺移植和心肺联合移植报告;重点主题:供受者大小匹配
J Heart Lung Transplant. 2019 Oct;38(10):1042-1055. doi: 10.1016/j.healun.2019.08.001. Epub 2019 Aug 8.
9
Outcomes in Lung Transplant Recipients With Mycobacterium abscessus Infection: A 15-Year Experience From a Large Tertiary Care Center.脓肿分枝杆菌感染的肺移植受者的预后:来自大型三级医疗中心的15年经验
Transplant Proc. 2019 Jul-Aug;51(6):2035-2042. doi: 10.1016/j.transproceed.2019.02.028. Epub 2019 Jul 11.
10
Management of infections due to nontuberculous mycobacteria in solid organ transplant recipients-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.实体器官移植受者中非结核分枝杆菌感染的管理——美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13588. doi: 10.1111/ctr.13588. Epub 2019 Jun 25.