食物不安全、营养不良与微生物组。
Food Insecurity, Malnutrition, and the Microbiome.
机构信息
Department of Pediatrics, Division of Gastroenterology, University of Minnesota, 2450 Riverside Ave, East Building, 6th floor, MB657, Minneapolis, MN, 55454, USA.
Department of Surgery, Division of Trauma and Surgery Critical Care, University of Louisville, Louisville, KY, USA.
出版信息
Curr Nutr Rep. 2020 Dec;9(4):356-360. doi: 10.1007/s13668-020-00342-0. Epub 2020 Nov 10.
Abstract
PURPOSE OF REVIEW
Food insecurity is defined as the disruption of food intake or eating patterns because of lack of money and other resources. Although a relationship between food insecurity and malnutrition would seem intuitive, this relationship remains unclear. This review was aimed at summarizing the emerging evidence of the relationship between food insecurity, malnutrition, and intestinal microbial changes.
RECENT FINDINGS
Evidence suggests that malnutrition is certainly associated with alteration in the intestinal microbiome. Alternative theories have been proposed as to the nature of the alteration, whether that be a result of microbial immaturity, dysbiosis, or contributions from both processes. Although the evidence continues to evolve, targeted nutritional therapies in conjunction with specific microbial therapy of probiotics or prebiotics may hold great promise for the treatment of malnutrition in the clinical and community settings.
摘要
目的综述
食品不安全是指由于缺乏金钱和其他资源而导致的食物摄入或饮食模式的中断。尽管食品不安全与营养不良之间的关系似乎是直观的，但这种关系仍不清楚。本综述旨在总结食品不安全、营养不良和肠道微生物变化之间关系的新证据。
最近的发现
有证据表明，营养不良肯定与肠道微生物组的改变有关。关于这种改变的性质，提出了一些替代理论，无论是微生物不成熟的结果，还是菌群失调，还是这两个过程的共同作用。尽管证据还在不断发展，但在临床和社区环境中，针对营养不良的靶向营养治疗与益生菌或益生元的特定微生物治疗相结合可能具有很大的前景。
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